PharmPK Discussion - Korsemeyer peppas constant

• On 13 Jun 2007 at 23:13:21, "satish jain" (satishpjain.at.gmail.com) sent the message
  

  
  Dear ,
  I have gone through the site, but still following things are not
  clear, please help me .
  I want to how to calculate diffusion index, release rate constant and
  K from Korsemeyer's equation.
  also please tell me how to decide on mechanism of drug release based
  on this equation.
  
  regards,
  Jain Satishkumar P.
  
  

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• On 14 Jun 2007 at 08:42:34, "K Ramarao" (kramarao.-a-.apotex.co.in) sent the message
  

  
  The following message was posted to: PharmPK
  
  Hi Satish,
  Have a look at the following articles; you may get the useful
  information:
  
  1. Costa P, Lobo JMS. Modeling and comparison of dissolution profiles.
        European Journal of Pharmaceutical Sciences, 2001, 13:123-133.
  2. Formulation and in vitro evaluation of ethyl cellulose microspheres
  containing
        Zidovudine.  Journal of Microencapsulation, December 2005; 22(8):
  863-876
  
  Regards,
  Rama Rao Kalakuntla,
  Apotex Inc.
  Bangalore.
  
  

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