Back to the Top
Does any know a reliable in vitro model for testing amount of drug
release/precipitation after subcutaneous injection. I want to try few
different formulations before testing it on animals.
Thanks
Bharat Dixit
Back to the Top
Dear Bharat,
You can use static-serial dilution approach to test precipitation of
a drug after subcutaneous/intramuscular injection.
You can refer following paper
Wu etal, Int. J Pharm. Vol. 304, (1-2), page 1-3
Want to post a follow-up message on this topic?
If this link does not work with your browser send a follow-up message to PharmPK@boomer.org with "Subcutaneous in vitro model" as the subject | Support PharmPK by using the |
Copyright 1995-2011 David W. A. Bourne (david@boomer.org)