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Can any of you provide any references or direction to find the
references for examples or reviews for altered PK, metabolism, or
metabolic enzymes/transporters in any animal disease models? Such as
diet-induced obesity mouse, zucker rat, or immunodeficient mouse (such
as nude mouse, with or without xenografted human tumor), etc...
Thanks a lot!
Huadong Tang, PhD
DMPK at Schering-Plough Research Institute
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