Back to the Top
dear all,i am working on sulpiride (a p-glyco protein substrate) i
want to know whether this drug is a biopharmaceutical classification
system class IV drug.The other thing when adminstered in the form of
self emulsifying drug delivery containing tween 80 a p-glyco protein
inhibitor there was an enhancement of bioavailability by around 2
folds what could be the reason. as some literature says solubility is
not an issue for poor bioavailability of sulpiride than what can be
the mechanism of increased bioavailability.But literature also says it
is a poorly water soluble drug.
Want to post a follow-up message on this topic?
If this link does not work with your browser send a follow-up message to PharmPK@boomer.org with "BCS sulpiride" as the subject
Support PharmPK by using the
Copyright 1995-2011 David W. A. Bourne (firstname.lastname@example.org)