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The following message was posted to: PharmPK
Hello,
I just want to post a follow-up message to the topic "Effect of
Hemolysis" as following;
I have the same problem as Prasad Tata but happened with rat plasma.
Hemolysis normally occurs in the first hour post-injection dose. I
have increased the injection time (via penile vein) to 55 seconds but
still have this problem. By the way, I have used 32% DMSO mixed with
saline to dissolve my compound. According to detail in another topic
relating DMSO as a solvent, this percentage should not result in
hemolysis.
Anybody have suggestion about this?
PhD candidate
Sansom Institute,
University of South Australia
Adelaide, SA
Australia
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