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For those of you that are interested in target tissue exposure, there
is a new article that you may find interesting: Saleem A, Price PM.
Early tumor drug pharmacokinetics in influenced by tumor perfusion but
not plasma drug exposure. Clin Cancer Res 2008;14(24):8184. They
conducted PET scans utilizing O15 labeled Co2/H20, radiolabeled DACA
and radiolabeled 50FU in 12 patients with cancer.
Carol Collins MD
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