Back to the Top
The following message was posted to: PharmPK
Simulations Plus launches Biorelevant Solubility Database.
Last year, we funded a series of experiments under the direction of Dr.
Rebecca Carrier at at Northeastern University to measure the solubilities of
160 drugs and drug-like molecules in three biologically relevant fluids:
fasted state simulated gastric fluid (FaSSGF), fasted state simulated
intestinal fluid (FaSSIF), and fed state simulated intestinal fluid
(FeSSIF). We also had aqueous solubility data for each compound.
Our original intent was only to use this data to build predictive models for
biorelevant solubilities into our ADMET PredictorT software and to support
the simulations we run with our GastroPlusT software. But the remarkably
strong interest expressed in the data makes it clear that the database
itself merits being a product in its own right. Therefore we have decided to
license the data to the industry at a price that is a fraction of the cost
to reproduce it, but one which we believe will generate sales well in excess
of our original investment. The license agreement will preclude the licensee
from redistributing the data in any form, including derivative works based
on the data.
For more information contact:
Mr. John DiBella
Manager, Marketing and Sales
Simulations Plus, Inc. (NASDAQ: SLP)
42505 10th Street West
Lancaster, CA 93534-7059
Phone: (661) 723-7723
FAX: (661) 723-5524
E-mail: john.dibella.aaa.simulations-plus.com or info.at.simulations-plus.com
Want to post a follow-up message on this topic?
If this link does not work with your browser send a follow-up message to PharmPK@boomer.org with "Biorelevant Solubility Database" as the subject
Support PharmPK by using the
Copyright 1995-2011 David W. A. Bourne (email@example.com)