PharmPK Discussion - Learning of pharmacokinetics

• On 6 Mar 2010 at 00:39:57, nimeshkumar patel (meetnimeshpatel.at.yahoo.co.in) sent the message
  

  
  Hi All,
  I am the beginner in the learning of pharmacokinetics. I want to understand mathematical processes in the pharmacokinetics.
  So, please give me the useful links or articles to understand maths in pharmacokinetics.
  
  With regards,
  Nimesh
  
  [See http://www.boomer.org/c/p4/
  and
  http://www.boomer.org/pkin/
  - db]
  
  

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• On 9 Mar 2010 at 00:02:00, "David S. Farrier" (DFarrier.aaa.SummitPK.com) sent the message
  

  
  The following message was posted to: PharmPK
  
  >Hi All,
  >I am the beginner in the learning of pharmacokinetics. I want to
  >understand mathematical processes in the pharmacokinetics.
  >So, please give me the useful links or articles to understand maths
  >in pharmacokinetics.
  >
  >With regards,
  >Nimesh
  
  Dear Nimesh,
  
  I think we all are beginners at one stage or another of learning
  pharmacokinetics.
  Good thing that evolution is slow enough for us to catch up.
  
  For an overview of some equations in pharmacokinetics, a popularly downloaded
  list can be obtained at:
  http://www.summitpk.com/equations/equations.htm
  
  There are also several links to introductory to advanced articles at
  our useful resource
  links page at:
  http://www.summitpk.com/links/links.htm#Pharmacokinetics
  
  I trust these references will give your a head start in your quest.
  
  Regards,
  
  David S. Farrier
  
  

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• On 9 Mar 2010 at 22:40:45, hatice duran (haticeduran99.-a-.yahoo.com) sent the message
  

  
  Dear Nimersh,
  
  I strongly advice you the following link. It is really useful to get a brief summary for PK!
  
  http://www.boomer.org/c/p1/
  [Thank you, a more up to date version is at
  http://www.boomer.org/c/p4/
  - db]
  
  You may also have a look at the following link:
  
  http://www.4um.com/tutorial/science/pharmak.htm
  
  Best regards;
  
  Pharm. Hatice Atkaya
  Regulatory Science Manager
  Bristol-Myers Squibb Company
  Turkey
  
  

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• On 11 Mar 2010 at 10:55:40, "Tarjinder Sahota" (tarjinder.z.sahota.-at-.gsk.com) sent the message
  

  
  The following message was posted to: PharmPK
  
  The original request was for information on the mathematical aspects of PK/PD modelling.  A couple of years ago, I was in the same position and I found the following useful.
  
  Pharmacokinetic-Pharmacodynamic Modeling and Simulation by Peter Bonate.
  
  It's mainly about the model building process, rather than the details of specific models. So if you're very new and need it all in a concrete setting in your mind, then I'd recommend getting some basic experience fitting PK/PD models with some maximum likelihood software (e.g. NONMEM) first.  It's less useful for fully Bayesian approaches (as opposed to maximum likelihood) or the very new fancy things you can do, but it'll set you up nicely for both of these.
  
  Tarj.
  
  [This and other PK books are listed at
  http://www.boomer.org/pkin/book.html
  - db]
  
  

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