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Dear ,
Please guide me the source for a list of low bioavailability drugs with bioavailability information and reason for low bioavailability (poor absorption or high first pass effect).
Thanks
Nigade Shirish U.
M. Pharm
Mumbai.
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Shirish,
You can get part of the requested info looking at the link below:
http://www.absorption.com/Site/Services/BCS.aspx
Greetings,
Dimiter
--
Dimiter Terziivanov, MD,PhD,DSc, Professor,
Univ Hosp "St. Ivan Rilski",
15 Acad. Ivan Geshov st, 1431 Sofia, Bulgaria
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The following message was posted to: PharmPK
Please, find out a list of drugs and their pk data in the pharmacology book of goodman and katsung. Regards, Daniel Rossi de Campos
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I need only data related to bioactive drugs of plant origin.
Tshar Prajapati
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Dear Mr.Tushar Prajapati,
I hope this will help.
Bioacive Compound Action/Clinical Use Plant Source
Acetyldigoxin Cardiotonic Digitalis lanata
Adoniside Cardiotonic Adonis vernalis
Aescin Anti-inflammatory Aesculus hippocastanum
Aesculetin Anti-dysentery Frazinus rhychophylla
Agrimophol Anthelmintic Agrimonia supatoria
Ajmalicine Circulatory Disorders Rauvolfia sepentina
Allantoin Vulnerary Several plants
Allyl isothiocyanate Rubefacient Brassica nigra
Anabesine Skeletal muscle relaxant Anabasis sphylla
Andrographolide Baccillary dysentery Andrographis paniculata
Anisodamine Anticholinergic Anisodus tanguticus
Anisodine Anticholinergic Anisodus tanguticus
Arecoline Anthelmintic Areca catechu
Asiaticoside Vulnerary Centella asiatica
Atropine Anticholinergic Atropa belladonna
Benzyl benzoate Scabicide Several plants
etc.
For the full table see the Source: http://www.rain-tree.com/plantdrugs.htm
Kindly go through the following articles which describes about the bioacive compounds of plant origin.
http://www.hort.purdue.edu/newcrop/proceedings1990/v1-491.html#Table%201
Antimicrobials of plant origin:
http://www.hort.purdue.edu/newcrop/proceedings1990/v1-491.html#Table%201
Thanks & Regards,
Dr.S.Gunasakaran, MD
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Please someone provide me list of low solubility drugs. For project work.
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