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I am beginning to investigate supersaturated SEDDS as an oral formulation for a novel compound I'm working on. I've developed supersaturated solutions with both cosolvents and lipid based SEDDS. However, because the compound is an oil at room temperature I'm having trouble explaining whether the compound has precipitated out (usually described by nucleation and crystal growth) or has the addition to the formulation to an aqueous environment (forming a milky like formulation) created an emulsion, because the drug doesn't exist in a crystal/solid form? Any opinions would be appreciated.
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