PharmPK Discussion - Caco-2 Permeability and Lymphatic transport

• On 14 Sep 2011 at 09:30:27, (sandipkuldharan.-at-.lupinpharma.com) sent the message
  

  
  The following message was posted to: PharmPK
  Dear All,
  
  Does Caco-2 permeability will correlate with compound absorbing through lymphatic transport?
  Is there any paper showing correlation of Caco-2 permeability and lymphatic transport?
  
  Thanks in advance
  
  Regards
  
  Sandip
  
  

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• On 22 Sep 2011 at 22:04:01, Jagannath Kota (jagannath.kota.-a-.gmail.com) sent the message
  

  
  Dear Sandip,
  
  Lymphatic transport is primarily passive due to the leaky structure of
  the peripheral lymphatics. Hence no correlation is expected between
  Caco-2 permeability and lymphatic transport,
  
  Regards, Jagannath
  
  

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