Back to the Top
Dear All:
We all know that well-stirred model is often used to connect CLint with
CLH, but when CLH is very close or even higher than QH, the well-stirred
model can not be used to calculate CLint. And at this time, the
dispersion model will be a better choice. But its equation was so
complicated that I can not know how to solve it and get CLint value from
CLH. Can anyone tell me how to solve this problem? Many thanks!
Jian
Want to post a follow-up message on this topic?
If this link does not work with your browser send a follow-up message to PharmPK@boomer.org with "CLint calculation using dispersion model" as the subject | Support PharmPK by using the |
Copyright 1995-2011 David W. A. Bourne (david@boomer.org)