Back to the Top
Does anyone have a reference(s) that demonstrate lower protein binding in the renally impaired caused by buildup of endogenous "waste materials"?
I know renal impairment is often accompanied by decreases in albumin and other proteins, but I'm interested to see if increases in BUN, creatinine, or other components can alter protein binding in these patients.
Thanks - Dave
Want to post a follow-up message on this topic?
If this link does not work with your browser send a follow-up message to PharmPK@boomer.org with "Literature reference for Protein Binding in Renal Impairment-Role of Endogenous Factors" as the subject
Support PharmPK by using the
Copyright 1995-2011 David W. A. Bourne (firstname.lastname@example.org)