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I am trying to work on algorithm for permeability of drugs into tissues
(not just intestinal permeability) for Permeability limited PBPK model.
Is there a way i could determine P for all tissues based on invivo
tissues and plasma data? I know we optimize it to estimate permeability
surface area in modeling. Is there a way to seperate P and SA from the
Also is the permeability dose dependent?
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