PharmPK Discussion - Bioequivalence studies of Omeprazole Magnesium MUPS tablets

• On 21 Mar 2012 at 08:53:05, Abhishek Srivastava (Abhishek.Sri.-at-.ranbaxy.com) sent the message
  

  
  The following message was posted to: PharmPK
  
  Please share me some literatures/ information on bioequivalence studies of
  Omeprazole Magnesium MUPS tablets. What could be the possible reasons for low
  Cmax? Does particle size plays a role? What about crystalline Vs Amorphous
  absorption?
  
  regards
  
  

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• On 21 Mar 2012 at 11:08:23, DRGUNA SAKARAN (drgunasakaran.-at-.gmail.com) sent the message
  

  
  Dear Mr.Abhishek Srivastava,
  
  You can find some scientific articles related to bioequivalence studies of
  Omeprazole Magnesium MUPS tablets in the below links.
  
  Schaltenbrand R, Huber R, Cotoraci CA, Mascher H, Potthast H, Hole U.
  Bioequivalence between omeprazole MUPS 20 mg as tablet and omeprazole MUPS 20 mg
  as tablet encapsulated in a hard gelatine capsule. Int J Clin Pharmacol Ther.
  2001 Oct;39(10):453-9.
  
  http://clinicaltrials.gov/ct2/show/NCT00889850
  
  Regards,
  Dr.S.Gunasakaran, MD
  Head - Clinical Research & Medical Affairs,
  Azidus, Clinical Research Organization, India
  www.clinicalresearchsociety.org/forum
  

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