PharmPK Discussion - Error message in ADAPT II

• On 12 Jul 2012 at 15:03:15, Alan Myers (alm_5c.-at-.yahoo.com) sent the message
  

  
  Hello,
  
  Our long-term goal is to do Bayesian modeling of cisplatin  PK in blood and
  peritoneal fluids.  But for the short-term (since we are new to this software
  package) we are following an example in the manual for MAP estimation and after
  repeated,repeated attempts can't seem to resolve this error message:
  
  "** Prior mean and covariance are 0 for all parameters - check Model File."
  
  Any suggestions/comments?
  

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• On 13 Jul 2012 at 00:19:00, "Lavigne, Jean" (jean.lavigne.-at-.celerion.com) sent the message
  

  
  The following message was posted to: PharmPK
  
  Dear Alan,
  
  In your model file, there is a subroutine called PRIOR were you need to put the
  mean vector and covariance matrix (upper or lower diagonal) as you're a priori
  Bayesian values.  Probably you did not filled this part in your model file.
  
  Jean
  

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