Pharmacokinetic-Pharmacodynamic AnalysisBack to the Top
An Introduction to Integrative Pharmacokinetic-Pharmacodynamic Analysis
By Johan Gabrielsson and Stephan Hjorth
PKPD awareness is vital if we are to attempt to relate preclinical results to
the acute and long term consequences in humans. The debate on whether
preclinical findings can be translated to the human usage is still engaging
scientists across industry, academia and regulatory bodies. Pharmacokinetics
(PK) and pharmacodynamics (PD) comprise traditionally distinct disciplines
within pharmacology, the study of the interaction of drugs with the body. This
book is written with a broad audience in mind and focuses on concepts.
Pharmacologists of all sorts, safety scientists, pharmacokineticists, medicinal
chemists, clinicians, statisticians, veterinarians, animal science
professionals, project leaders and students of medical, pharmaceutical and
veterinary sciences are the primary targets.
*introduces the basics of PK and PD concepts
*outlines the implications of integrating PK and PD analysis
*introduces the principles behind different biomarkers and inter-species scaling
*discusses experimental design of PK, PD and safety studies in non-human species
*covers numerous real life Case Studies from the drug discovery arena.
264 pages. Illustrated in colour. ISBN 9789197945233.
Make your order from our webshop at www.lma-books.se or by e-mail to
Project Manager, M Sc Pharm
Swedish Academy of Pharmaceutical Sciences
PO Box 1136, SE 111 81 Stockholm, Sweden
[This and other PK books are listed at http://www.pharmpk.com/book.html - db]
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