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Does anyone have any experience about combination of different brands of drugs (generic and / or
original) in transplant patients (in the same patient, in the same administration)?
For instance dose 75 mg (per dose) twice daily, but in combination: CYA trademark "A" 50mg + CYA
trademark "B" 25mg
Medium and/or long term clinical outcome?
Variability in the estimation of pharmacokinetic parameters?
Predictability of blood levels / pharmacotherapeutic regimens?
Thank you!
Paulo Caceres Guido
Clinical Pharmacokinetics Unit
Garrahan Pediatric Hospital
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