PharmPK Discussion - Non Linear Covariate Analysis in Phoenix NLME

• On 20 Aug 2014 at 08:17:01, Izna Ali (iznaali.-a-.UNC.EDU) sent the message
  

  
  Hi everyone,
  
  Does anyone have any experience with coding exponential covariates in Phoenix using QRPEM? According
  to the User Guide "models with non-linear covariate models can be easily handled in QRPEM by a
  simple manual restructuring of the text model so the non-linear covariate model is applied outside
  of the initial structural parameter definition rather than inside". However, I am not really sure
  how to go about doing that. If anyone has any examples or advice it would be greatly appreciated!
  
  Thanks,
  Izna
  
  iznaali.-at-.unc.edu
  
  

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• On 20 Aug 2014 at 11:08:44, Bob.Leary.at.Certara.com sent the message
  

  
  Please contact me directly if you are interested - I can provide some WORD-based documentation that
  illustrates the technique for dealing with non-linear covariate models in Phoenix NLME QRPEM (it
  also works for time-varying covariates)
  
  Bob Leary
  Bob.Leary.at.Certara.com
  
  

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