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To support evaluation of selectivity of an immunoassay, I’d like to solicit information on the
(relative) abundance of the olanzapine metabolites.
Although the mas balance study suggests that 80% of radioactivity is associated with metabolites,
the abundance of well-documented metabolites (10-N-glucuronide, 4'-N-desmethyl olanzapine, N-oxide,
) does not fill the gap.
Any information on other metabolites, e.g. 2-OH-methyl-olanzapine, 2-carboxy olanzapine,
N-desmethyl-2-carboxy-olanzapine, 2-carboxy olanzapine glucuronide etc?
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