PharmPK Discussion - Search for Compendium of Cytochrome P450 drug interactions

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On 3 Nov 1995 at 10:00:34, JPaul78008.-a-.aol.com sent the message


Is there a compendium available of cytochrome P450 isoenzyme interactions
with various drugs?  Is there one that is in progress ?  There are many
articles in this growing field, but I am looking for a complete, but simple
table that lists  drugs and P450 isoenzyme interactions (ie inhibit, enhance,
induce, etc).

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On 3 Nov 1995 at 15:58:52, "Budris, Bill" (BBudris.at.nmh.org) sent the message


There is a list by S. Saklad, Pharm.D. at
http://saklad.uthscsa.edu/CYP_and_Drugs.html, which he apparently took from:
 Antidepressants and Cytochrome P450 Enzyme Involvement (DeVane CL. J Clin
Psychiatry 1994;55[12Suppl]:38-45.

I have heard that there is a table in a recent '95 Clinical Pharmacokinetics
article by Preskorn and Magnus: I haven't been able to get the complete
citation yet, but if anyone else knows I'm interested too.

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