PharmPK Discussion - ADAPT II prior estimates

• On 27 Aug 1996 at 11:54:10, Paul Laub (P_Laub.at.fccc.edu) sent the message
  

  
  Hello,
  
      In using the MAP module of ADAPT II (release 3), does anyone know if prior
  means and covariances for initial conditions can be incorporated into
  subroutine PRIOR just as means and covariances of system parameters are? It
  seems to me that this should be the case as differential equation model
  fitting with ADAPT II can estimate initial conditions as well as system
  parameters.  However, I find nothing in the manual regarding this. For
  example, what element of array Pmean in subroutine PRIOR would be set to the
  mean of initial condition one?
  
  Thanks. Paul B. Laub
                                 - 30 - 30 - 30 -
  Paul B. Laub        numerical analysis and mathe. modeling of biomedical data
  Dept. of Medical Oncology                                      328 West Bldg.
  Fox Chase Cancer Center        7701 Burholme Ave.         Phila. PA 19111 USA
  p_laub.aaa.fccc.edu                (215)728-4743 (voice)     (215) 728-2741 (fax)
  
  

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