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Subject:Pharmacokinetics's experiments.
Keywords:experiments results of acetylsalicylic acid and salicylic acid
(ASPEGIC).
Topics:
We are interested in modelisation and simulation of pharmacokinetics:
absorbtion, tissue distribution and release of acetylsalicylic acid and
salicylic acid (ASPEGIC).
We would be interested in any information and references to papers
discussing the clinical studies as well as laboratory.
You can send E-mail message to ainaoui.at.univ-st-etienne.fr
Thank you in advance.
Yours truly. A.AINAOUI
My address is as follows:
*-----------*
* M. Abdelkader AINAOUI *
* Universite Jean Monnet *
* Laboratoire de Chimie des Materiaux *
* et Chimie Industrielle, *
* 23, rue Dr. P. Michelon *
* 42023 ST-ETIENNE CEDEX 2 FRANCE *
* Phone: 77-42-15-00 (post 25-21 labo) *
* 75-32-47-58 (home) *
* Fax: 77-42-15-75 (labo) *
* Email: ainaoui.aaa.univ-st-etienne.fr *
*-----------*
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On Fri, 26 Apr 1996, AINAOUI Abdelkader wrote:
> Subject:Pharmacokinetics's experiments.
> Keywords:experiments results of acetylsalicylic acid and salicylic acid
> (ASPEGIC).
>
> Topics:
>
> We are interested in modelisation and simulation of pharmacokinetics:
> absorbtion, tissue distribution and release of acetylsalicylic acid and
> salicylic acid (ASPEGIC).
This is for the dog
Chen, C. N.
Coleman, D. L.
Andrade, J. D.
Temple, A. R.
1978
Pharmacokinetic model for salicylate in cerebrospinal fluid, blood,
organs, and tissues
Journal of Pharmaceutical Sciences
67:38-45
Susan E. Shoaf, PhD
shoaf.at.clinpharm.niaaa.nih.gov | National Institute on Alcohol Abuse and
I don't speak for NIAAA, | Alcoholism
that's for the PR office. |
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We are interested in modelisation and simulation of pharmacokinetics:
absorbtion, tissue distribution and release of acetylsalicylic acid and
salicylic acid (ASPEGIC).
*-----------*
* M. Abdelkader AINAOUI *
* Universite Jean Monnet *
* Laboratoire de Chimie des Materiaux *
* et Chimie Industrielle, *
* 23, rue Dr. P. Michelon *
* 42023 ST-ETIENNE CEDEX 2 FRANCE *
* Phone: 77-42-15-00 (post 25-21 labo) *
* 75-32-47-58 (home) *
* Fax: 77-42-15-75 (labo) *
* Email: ainaoui.-a-.univ-st-etienne.fr *
*-----------*
Reference:
Aarons, Hopkins, Rowland, Brossel and Thiercelin
Pharmaceutical Research 1989 vol 6 (no.8) p660
Routes of administration and sex differences in the pharmacokinetics of
aspirin, administered as its lysine salt.
This is a paper describing a study performed at Medeval Ltd, in Manchester,
England, in conjunction with Synthelabo, Paris, which may be of use.
Further information regarding Medeval can be obtained via the WWW:
http://www.man.ac.uk/vuman/med.htm
John Davis
Pharmacokineticist
Medeval Ltd
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Dear Dr. Ainaout,
You can find relevant information in our recent article:
D. Dubovska, V.K.Piotrovskij et al. Pharmacokinetics of
acetylsalicylic acid and its metabolites at low doses: A compartmental
modeling. Meth Find Exp Clin Pharmacol, 1995, 17(1): 67-77.
There is there a lot of references to earlier publications about ASA,
SA and other metabolites kinetics in man.
Best regards,
V. Piotrovskij
--------
Vladimir Piotrovskij, Ph.D. Fax: +32-14-603768
Janssen Research Foundation Email: vpiotrov.at.janbe.jnj.com
Clinical Pharmacokinetics
Turnhoutseweg 30
B-2340 Beerse
Belgium
from: "Vladimir Piotrovskij"
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[Second request for info - db]
Dear sir,
I want to post this question to the PharmPK listserv.
I'am a Ph.D. student. My research interests are:
* Applied computer science, applied mathematics and numerical analysis.
* Simulation and modelisation of pharmacokinetics.
* Oral, intraveneus and intramuscular administration.
* Controlled drug release of oral dosage forms.
I would be grateful if you would send me more information about the
experiments concerning the ASPEGIC "acetylsalicylic acid and salicylic acid".
Thanks in advance.
Yours truly. A.AINAOUI
My address is as follows:
* Address: *
* Abdelkader AINAOUI *
* Universiti Jean Monnet *
* Laboratoire de Chimie des Matiriaux *
* et Chimie Industrielle *
* 23, rue Dr. P. Michelon *
* 42023 ST-ETIENNE CEDEX 2 *
* Phone: 77-42-15-00 (post 25-21 labo) *
* 75-32-47-58 (home) *
* Fax: 77-42-15-75 (labo) *
* Email: ainaoui.-at-.univ-st-etienne.fr *
* http://www.univ-st-etienne.fr/~lcmci/ainaoui.html *
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