PharmPK Discussion - Aspirin bioavailability

• On 2 Dec 1996 at 10:24:50, Bradley Hein (Bradley.Hein.aaa.UC.Edu) sent the message
  

  
  Hello,
  
  I am a first year pharm. D student who is researching a project
  comparing 81 mg aspirin doses brand name vs. generic brands (enteric
  coated).  I have heard that there might be some biavailability problems
  with the generic enteric coated aspirin products, but I haven't been able
  to find any real data on this. Does anyone have any suggestions?
  
  Thanks ahead of time,
  Brad Hein, RPh
  
  

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• On 3 Dec 1996 at 14:17:41, "Dr. James Axelson" (axelson.-a-.unixg.ubc.ca) sent the message
  

  
  Dear Bradley,
  
  you might try to search the issue of aspirin kinetics under the name of
  Gerhard Levy, PharmD, He "wrote the book" on the issue of aspirin
  kinetics, dosage form effects, absorption, etc.
  
  Best Regards
  
  Jim Axelson
  
  

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• On 3 Dec 1996 at 17:15:01, "Arasb Ateshkadi, Pharm.D." (arasb.aaa.deans.pharm.utah.edu) sent the message
  

  
  You may have already thought of this, but have you referred to the
  OTC handbook (by APhA)? Since this is a referenced text, it may
  contain the citation for your question. Good luck.
  
  Arasb Ateshkadi, Pharm.D.
  Assistant Professor
  Department of Pharmacy Practice
  College of Pharmacy
  University of Utah
  258 Skaggs Hall
  Salt Lake City, UT 84112
  TEL: (801) 581-6159
  FAX: (801) 585-6160
  e-mail: arasb.aaa.deans.pharm.utah.edu
  
  

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• On 4 Dec 1996 at 10:45:00, Steve Ebert (sebert.at.facstaff.wisc.edu) sent the message
  

  
  It's my impression that companies making generics must file data with the
  FDA to prove bioequivalence.  You might consider calling the companies and
  having them send you a copy of the report they filed with FDA.
  
  Steven C. Ebert, Pharm.D., FCCP
  Clinical Specialist, Infectious Diseases
  Clinical Associate Professor of Pharmacy
  Department of Pharmacy, Meriter Hospital
  202 S. Park Street
  Madison, WI  53715
  Ph: (608)-267-6035
  Fx: (608)-267-6022
  
  

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