PharmPK Discussion - Betaxolol, pKa?

• On 10 Jan 1996 at 10:00:47, mbxsaettone.-at-.mail.cnuce.cnr.it (Marco Fabrizio Saettone) sent the message
  

  
  Could anybody indicate me the pKa value of Betaxolol, and/or the relevant
  literature?
  Many thanks, and  best New Year wishes to the whole list.
  M. Fabrizio Saettone
  
  M. Fabrizio Saettone
  Professor of Pharm. Technology
  Dept. of Pharmaceutical Sciences,
  University of Pisa
  Via Bonanno 33
  I- 56126  PISA (Italy)
  Phone: +39-50-24000  or  +39-50-29324
  Fax:   +39-50-21002
  E-Mail:   mbxsaettone.-a-.mail.cnuce.cnr.it
  
  

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• On 10 Jan 1996 at 15:35:08, "Jane Knight" (jknight.aaa.ovcnet.uoguelph.ca) sent the message
  

  
  A 2% solution of betaxolol in water has a pH of 4.5 to 6.5. This is from the
  Martindale 30th edition pharmacopoeia. No pKa listed. Hope this helps.
  
  Jane Knight, B.Sc. Phm.
  Pharmacy Administrator
  Ontario Veterinary College
  University of Guelph
  Canada N1G 2W1
  (519) 824-4120 ext. 4143
  jknight.-a-.ovcnet.uoguelph.ca
  
  

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• On 11 Jan 1996 at 10:24:11, rborne.aaa.sunset.backbone.olemiss.edu (Dr. Borne) sent the message
  

  
  The AHFS Drug Information 94 p 1855 lists the pKa of betaxolol HCl as 9.38
  
  from: rborne.aaa.sunset.backbone.olemiss.edu (Dr. Borne) (by way of Douglas
  Anderson )
  
  

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