PharmPK Discussion - General PD book reference

• On 5 Dec 1996 at 10:50:37, VANDENHENDE Francois (VANDENHENDE_FRANCOIS_R.aaa.Lilly.com) sent the message
  

  
  Does anyone has good references on principles, design, responses
  definition, modelling and statistical analyses of pharmacodynamic studies.
  
  Thanks,
  
  Francois
  -------------------
  Francois Vandenhende
  Statistician
  Lilly Research Laboratories
  MSG - Belgium
  Francois.-a-.lilly.com
  +32-10476469
  
  

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• On 8 Dec 1996 at 18:29:19, rajesh krishna (rkrishna.aaa.unixg.ubc.ca) sent the message
  

  
  >
  > Does anyone has good references on principles, design, responses
  > definition, modelling and statistical analyses of pharmacodynamic studies.
  
  There are several texts in pharmaceutical statistics.  For clinical
  trials or otherwise, a couple of good books are:
  
  [1]  Planning pharmaceutical clinical trials:  basic statistical
  principles.  William M. Wooding
  [2]  Statistical methodology in the pharmaceutical sciences.  Donald A.
  Berry.
  
  Raj
  
  

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• On 8 Dec 1996 at 18:31:05, Nick Holford (n.holford.at.auckland.ac.nz) sent the message
  

  
  > Does anyone has good references on principles, design, responses
  > definition, modelling and statistical analyses of pharmacodynamic studies.
  
  You might want to look at:
  
  Van Boxtel et al. "The In Vivo Study of Drug Action". Elsevier 1992
  
  This book attempted to cover most of what you ask for but of course it
  is now 5 years old. Principles havent changed much however.
  
  --
  Nick Holford, Dept Pharmacology & Clinical Pharmacology
  University of Auckland, Private Bag 92019, Auckland, New Zealand
  email:n.holford.-a-.auckland.ac.nz tel:+64(9)373-7599x6730 fax:373-7556
  http://www.phm.auckland.ac.nz/Staff/NHolford/nholford.html
  
  

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