PharmPK Discussion - Species Comparison and administration route

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On 24 Apr 1996 at 12:24:04, (nrt.aaa.pond.com) sent the message


Perhaps someone can help me locate the following:

We often attempt to rationalize PK data across
several species.  Sometimes we try to
rationalize PK  data, from the same species
using differing administration routes.

Can anyone suggest a reference comparing
PK data across a subset of mice-rats-beagle dogs-macaque monkeys.
and/or
mice or monkeys dosed by subcutaneous vs. IV.  vs. peroral.
We would be interested in corticosteroids.

RSVP posting or email would be appreciated.
Many thanks,

Nathan Tzodikov, Ph. D.
Magainin Pharamaceuticals
Plymouth Mtg. PA
610-941-5252
nrt.aaa.pond.com

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On 25 Apr 1996 at 11:12:47, Prasad Tata (Prasadt.-a-.OTSUKA.OAPI.COM) sent the message


A person who can help you in this regard is

Dr. Harold Boxenbaum
Distinguished Scientist
Otsuka America Pharmaceuticals Inc.
2440 Research Blvd.
Rockville, Md 20850

Tel:(301) 5274821

Good Luck

Prasad Tata, Ph.D.

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