PharmPK Discussion - Thalidomide Therapeutic Range

• On 24 Oct 1996 at 10:39:53, Carlo Marra (cmarra.-at-.unixg.ubc.ca) sent the message
  

  
  I was wondering if anyone knew of an "accepted" therapeutic range of
  thalidomide for bone marrow transplant recipients (and any references
  pertaining to this range)?
  
  THanks
  Carlo Marra, B.Sc.(Pharm.), Pharm.D.
  Clinical Pharmacy Specialist/Clinical Drug Research
  Dept. of Pharmacy
  Vancouver Hospital and Health Sciences Centre
  855 West 12th Ave.
  Vancouver, B.C V5Z 1M9
  Clinical Assistant Professor
  University of British Columbia
  Vancouver B.C., CANADA
  ph: (604) 875-4077
  fax: (604) 875-5267
  
  

  Back to the Top

• On 25 Oct 1996 at 09:44:16, rajesh krishna (rkrishna.-at-.unixg.ubc.ca) sent the message
  

  
  >
  > I was wondering if anyone knew of an "accepted" therapeutic range of
  > thalidomide for bone marrow transplant recipients (and any references
  > pertaining to this range)?
  
  As such, I doubt if there is an "accepted" therapeutic range.  A couple
  of articles have had successes in this vein:
  [1]  Forsyth, CJ et al., Thalidomide responsive chronic pulmonary GVHD.
  Bone Marrow Transplantation. 17(2), 291-293, 1996.
  [2]  Cole, CH et al., Thalidomide in the management of chronic GVHD in
  children following bone marrow transplantation.  Bone Marrow
  Transplantation.  14(6), 937-942, 1994.
  You could also call up the BMT unit at the BC Cancer Agency and/or the BC
  Children's Hospital to see what range they are using.
  
  Rajesh Krishna
  
  

  Back to the Top

Copyright 1995-2014 David W. A. Bourne (david@boomer.org)