Back to the Top
See
Author
Anonymous.
Title
Study finds implantable pump effectively suppresses recurrent
osteomyelitis infection.
Source
Pharmacy Practice News. 14(Jul): p 8-9. 1987.
Abstract
A study in 21 patients, aged 20-59 yr, with osteomyelitis treated
with
either amikacin (19 patients) or netilmicin (2 patients)
administered by
an Infusaid pump implanted subcutaneously, is briefly described.
Wound drainage ceased in all patients during therapy. Following
pump
removal, 2 patients immediately resumed draining; 3 others resumed
draining at 2, 11, and 18 months. The other 16 did not have resumed
draining.
Side effects of the pump antibiotics have been minor. Two patients
showed
some nephrotoxicity as reflected in a fall in creatinine clearance
following therapy to below 70 ml/min, but in neither
patient--during or
after therapy--did their serum creatinine exceed the upper limits
of
normal.
Author
Doutre, MS. Beylot, C. Vendeaud-Busquet, M. Bioulac-Sage, P.
Institution
Serv. de Dermatologie Hopital du Haut Leveque, CHU de Bordeaux,
33604
Pessac, France.
Title
Cutaneous necrosis following subcutaenous administration of
gentamicin.
Source
Therapie. 40(Jul-Aug): p 266-267. 1985.
Abstract
Cutaneous necrosis due to subcutaneous injection of gentamicin
sulfate
(Gentalline), 80 mg thrice daily for 8 days, in a 67-yr-old woman
on
anticoagulant therapy was reported. (4 refs.)
********************************
Randy Trinkle, BScPharm, BA
Dept. of Pharmacy
Dawson Creek & District Hospital
Dawson Creek, BC
mailto://rtrinkle.-a-.pris.bc.ca
********************************
Every now and then when your life gets complicated...
HST
PharmPK Discussion List Archive Index page
Copyright 1995-2010 David W. A. Bourne (david@boomer.org)