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We have conducted a retrospective population study of gentamicin in horses.
We have fitted the data according to a two-compartment model with weight and
serum creatinine as the significant covariates for V1 and Cl in the final
model. What is the best way to derive dosage recommendations from this
population model?. Can this be done with NONMEM?. If not, what other
packages may I use for the simulations?
I appreciate your help.
Tomas Martin-Jimenez, DVM
FARAD East Regional Center
North Carolina State University
College of Veterinary Medicine
4700 Hillsborough St
Raleigh NC 27606
Ph: (919) 821-9519, 829-4398
Fax: (919) 829-4358
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