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I am currently interested in the intracellular PK of galactosylated
proteins. I intend to investigate the fate of those proteins after being
endocytosed by hepatocyte (i.e. endosomal sorting, lysosomal proteolysis,
biliary excretion etc.).
Does anyone have any experience with this topic? Any comments on methodology
(subcellular fractionation, PK evaluation.......) or literature sources are
Dept. Drug Del. Res.
Faculty of Pharmaceutical Sciences
PharmPK Discussion List Archive Index page
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