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Plasma NO levels are usually quantitated indirectly by measurement of the
end products of nitric oxide oxidation (nitrite and nitrate). This method
was first described by Green et al in 1982. It is still used in clinical
studies to date (Gomez-jimenez et 1995, Endo et al 1996).
Green et al.(1982) Analysis of nitrate, nitrite and [N] nitrate in
biological fluids. Anal Biochem 126, 131-138.
Gomez-Jimenez et al (1995) L-arginine: nitric oxide pathway in endotoxemia
and human septic shock. Crit Care Med 23, 253-258.
Endo et al (1996) Nitrite/nitrate oxide (NOX) and cytokine levels in
patients with septic shock. Research Communications in Molecular
Pathology Pathology and Pharmacology 91, 347-355.
Tristan Maurer Pharm.D.
State University of New York at Buffalo
PharmPK Discussion List Archive Index page
Copyright 1995-2010 David W. A. Bourne (firstname.lastname@example.org)