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Dear Koumara,
L-dopa might suit your needs.
Sri
Srikumaran Melethil, Ph.D.
Professor of Pharmaceutics and Medicine
University of Missouri-KC
School of Pharmacy
Room 203-B, 5005 Rockhilll Road
Kansas City, MO 64110
816-235-1794 (fax: 816-235-5190)
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These are some of the drugs which are metabolized both in the
gastrointestinal tract and liver. They usually tend to be high clearance
drugs that are substrates of P450 3A4.
Cyclosporin
Verapamil
HIV protease inhibitors.
There are many more but the above three are the ones which are quoted most
frequently.
Regards.
Aziz Karim
aakari.aaa.msn.com
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Hello
Is there anybody who could suggest literature on studies of elimination of
Plumbagin and Emetine in Humans. We are developing certain herbal
formulations with plants where these two compounds seem to be present in
significant percentage. If anyone can throw more light on these two
compounds it will be highly appreciated.
Dr. P. M. Murali
Dalmia Centre For Biotechnology
Coimbatore India
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I'd contact the manufacturer of Emitine, even though the drug has been off
the US market for sometime........Pfizer-Roerig used to market Emitine in the
US
Hank Resnick, RPh, MS
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