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What is the consensus re statistical review of raw and derived data? I
would appreciate your comments on the following:
1. Shouldn't raw clin obs, clin path and bioanalytical data (incl PK) be
examined to determined the kind of statistical test appropriate (non
parametric vs parametric analysis) and transformed if necessary (ratios
2. Before applying ANOVA or t test should the variance of the groups to
be compared be examined?
3. Shouldn't bioanalytical data be reported ( and used in PK)only for
values above the ELOQ (or LOQ).
Thanks for your time and consideration.
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