PK/PD and Other Jobs

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Contact email address: broseberry@cartermackay.com - 30th Jul 202 [3011]

New roles available, bay area CA, level flexible. Relo provided, also flexible during COVID.

This position will assist in developing and applying clinical pharmacology and translational medicine strategies for candidate drug products including from FIH through late stage development and regulatory filing using PK, PD, DMPK, and drug therapeutic principles, and knowledge of drug development processes and regulatory guidance.

A Pharm. D. or PhD in a scientific discipline is required. Post-doctoral work may serve as experience. non-PhDs with demonstrated capabilities and/or significant experience may also be considered. Must be able to demonstrate significant success in technical proficiency, scientific creativity, collaboration with others and independent thought and be able to clearly communicate scientific and technical information both written and oral. Experience working in an regulated environment and experience and understanding of ICH, and GCP is highly desired. Must have hands-on experience with data analysis, non-compartmental and compartmental PK/PD and using data processing software such as Phoenix WinNonlin, R, NONMEM, etc. Good working knowledge of graphing software is also desired.
Contact email address: broseberry@cartermackay.com - 29th Jul 202 [3010]

New role available! Full time, level flexible. Can work remotely to start. email me for more info:

Sr. Scientist/Manager/Associate Director Quantitative Clinical Pharmacology

responsible for providing quantitative clinical pharmacology and pharmacometric deliverables for clinical development assets from phase I-III. The individual will prepare and develop clinical pharmacology plans including dose selections and predictions using mathematical and statistical models to study complex interactions between drugs, patients, and biological systems to understand disease progression and the impact of patient stratification on disease progression.

Primary Responsibilities Include:

Education and Skills Requirements:
Contact email address: telder@stem-sourcing.com - 28th Jul 202 [3009]

The Director level clinical pharmacologist/pharmacokineticist in the Department of Translational Medicine and Early Stage Clinical Development plays a central role in both clinical development and in support of nonclinical development. He/she will represent Clinical Pharmacology function and provide subject matter expertise on cross-functional project teams. He/she will assist in directing the clinical pharmacology development plan, synopsis preparation, clinical phase oversight, and reporting, and provide leadership of a multifunctional study team focused on clinical studies through design, delivery, and reporting, as well as ensuring scientific accountability. He/she will mentor junior and senior level scientists in the department in addition to being an individual contributor.

A core scientific responsibility is ensuring optimal doses and dosage regimens in patients, and as such, the successful candidate must be able to integrate the knowledge of PK/PD, quantitative modeling and simulation, drug development, TK, and nonclinical PK (ADME and DMPK). Working within the clinical development organization, the Director role supports multiple programs through participation on internal project working teams and serves as a liaison between chemistry, life sciences, regulatory and clinical operations.

Essential Areas of Responsibility: The incumbent may design, conduct and/or manage internal and external IND-enabling studies (eg: in vitro and in vivo nonclinical metabolism and PK), design and review clinical pharmacology study protocols and support clinical trials, conduct pharmacokinetic/pharmacodynamic modeling and analyses, and incorporate findings into study report and regulatory documents as well as participate directly in regulatory interactions. A strong background in clinical pharmacology and pharmacokinetics combined with excellent leadership and communications skills are essential in this dynamic role. Clinical pharmacology experience with both small and large molecules in a variety of clinical investigation paradigms (eg: adaptive trial design) is desired. Direct experience with pharmacokinetic/pharmacodynamic modeling, bioanalytical analysis, and nonclinical ADME are desirable attributes. Knowledge of, and immediate experience in the area of CNS and/or oncology therapeutics is desired.

The candidate is expected to be an active contributor to the multi-disciplinary project teams, providing innovative and progressive thinking to projects and where appropriate guidance to other team members. Upon completion of on-boarding, this person will be relied upon to act independently, within a highly matrixed clinical development organization and must have the experience and conviction to provide sound clinical pharmacology related input to the project teams.

Minimum Education & Experience Requirements:

External website https://www.stem-sourcing.com


Contact email address: cornelia.boehnstedt@fu-berlin.de - 16th Jul 202 [3008]

Call for applications within the interdisciplinary PhD program PharMetrX

The Graduate Research Training Program PharMetrX: Pharmacometrics & Computational Disease Modelling is an interdisciplinary PhD program bridging pharmacy and mathematics. It aims at understanding the drug-patient-disease interaction by analysing data of drug concentration, effect & disease profiles of pre-/clinical trials and of therapeutic care by developing and using mathematical & statistical models.

We are currently inviting applications to enrol in the PharMetrX Research+ Program or the PharMetrX Training+ Program.

The PharMetrX Research+ Program (Research & Training & Network) comprises an excellent research environment in the vibrant Berlin/Potsdam area, fascinating and innovative research projects in a highly relevant field, truly transdisciplinary supervision, an individual mentorship from one of the associated industry partners, a specifically tailored training program of compact modules, a network of peers and a highly competitive 3.5 years fellowship.

The PharMetrX Training+ Program (Training & Network) offers a specifically tailored training program of compact modules that convey the foundations in pharmacokinetics & pharmacodynamics, systems biology, statistics, methodological approaches of modelling & simulation etc. as well as a network of peers. It is open for PhD students who have already started their PhD in the field of pharmacometrics or will do so soon.

Both programs are open to candidates with a university degree in pharmacy, pharmaceutical sciences, mathematics/statistics, bioinformatics, life sciences or medicine. See https://www.PharMetrX.de for further details.

Deadline for applications: 15 September 2020.

PharMetrX is a joint program of Freie Universität Berlin and the Universität Potsdam, supported by a consortium of global research-driven pharmaceutical companies.

Charlotte Kloft & Wilhelm Huisinga Program Chairs

External website https://www.PharMetrx.de


Contact email address: Filippos.Kesisoglou@Merck.com - 30th Jun 202 [3007]

Senior Scientist - Biopharmaceutics, Pharmacokinetics

Please see link here:
https://jobs.merck.com/us/en/job/R60517/Senior-Scientist-Biopharmaceut
Our team is looking for a strong candidate for the position of Senior Scientist to support biopharmaceutics assessment across delivery modalities. The successful candidate will be responsible for representing the biopharmaceutics team in drug product development teams, driving the biopharmaceutics strategy, while helping to develop the next generations of physiologically-based modeling and simulation tools.

Primary Responsibilities:
Proactively identifying key biopharmaceutics risks at each stage of drug product development, conducting hypothesis-based assessment employing an integrated approach, driving the development of in vitro-in vivo relationship and preclinical-to-clinical translation in bioperformance of formulations. Developing physiologically-based pharmacokinetic models to facilitate decisions in areas including formulation development, food effect evaluation, in vitro-in vivo correlations and dissolution specification setting. Leading and participating in both internal and external innovation in the fields of biopharmaceutics and modeling.

Education Minimum Requirements:
PhD in Pharmaceutics, Pharmacokinetics or Pharmaceutical Sciences Masters in Pharmaceutics, Pharmacokinetics or Pharmaceutical Sciences with at least 5 years of industry experience.

Required Experience and Skills:
Advanced coursework in pharmacokinetics and understanding of principles of physiologically-based pharmacokinetic modeling. Demonstrated strong proficiency in PK, PK/PD or popPK modeling (e.g., coding in NONMEM, R, MATLAB, Python, Phoenix) Strong influencing and communication skills and demonstrated ability and creativity in solving tough problems. A track record of scientific publications in the field.

Preferred Experience and Skills:
Hands-on experience with physiologically-based pharmacokinetic modeling software (e.g., Simcyp, GastroPlus) is highly desired. Familiarity with advanced use of PK, PK/PD, PBPK/PD models is a plus Experience with applying such models to specialized dosage forms (oral and non-oral extended release, inhaled, others)

External website https://jobs.merck.com/us/en/job/R60517/Senior-Scientist-Biopharmaceut


Contact email address: jchapman@haallc.com - 24th Jun 202 [3006]

Senior Director of Pharmacometrics

Key Responsibilities

Experience Level

External website https://haallc.com/career-opportunities


Contact email address: gobeaun@mmv.org - 19th Jun 202 [3005]

PKPD Translational Medicine Scientist (post-doc fellowship)

JOB PURPOSE

Medicines for Malaria Venture (MMV) is a leading product development partnership (PDP) in the field of antimalarial drug research and development. Its mission is to reduce the burden of malaria in disease-endemic countries by discovering, developing and delivering new, effective and affordable antimalarial drugs.

This 3-year post-doctoral fellowship will provide a PhD graduate with the opportunity to expand their scientific knowledge and skills, to see how pharmacometric approaches (PBPK and PK/PD) are used to speed up the drug development process, from early to late stage and to contribute to the development of innovative modeling approaches.

PRIMARY DUTIES AND RESPONSIBILITIES:

EDUCATION AND EXPERIENCE:

LOCATION: Geneva, Switzerland

MORE INFORMATION AND APPLICATION: on https://www.mmv.org/about-us/work-us/jobs#op-395680-pkpd-translational-medicine-scientist-postdoc-fellowship MMV website

External website https://www.mmv.org/about-us/work-us/jobs#op-395680-pkpd-translational-medicine-scientist-postdoc-fe


Contact email address: cornelius.amberger@merckgroup.com - 3rd Jun 202 [3004]

Associate Scientific Director Discovery NCE DMPK (all genders)

Your role:
We are seeking an experienced Scientific Director to join our Discovery DMPK team Darmstadt. As Scientific Director you will champion and develop new scientific ideas and concepts specifically focused on DMPK-related activities. This will include scientific excellence and validation of in vitro, in vivo and in silico DMPK assays. You will provide support for external opportunity evaluations. The role coaches peers and contribute to maintaining a strategic network within and outside. You will provide scientific input to DMPK strategic goals and contribute to the overall goal of Discovery DMPK of selecting high quality molecules to advance in our pipeline. The Scientific Director will collaborate with the Development DMPK teams to ensure that the right development studies are conducted to manage risk and de-risk identified liabilities. The role will have good understanding of PK/PD models preferentially with hands-on experience in using them to support discovery projects.

You will be DMPK representative in project teams and support projects from concept generation up to selection of development candidates (and beyond when needed). As project representative, you will identify DMPK related key issues in Discovery projects and provide inputs to the design of new molecules to address these issues. The Scientific director will compile DMPK data to predict human PK, and in collaboration with other relevant disciplines (Clinical Pharmacology, Discovery Pharmacology, Safety, Formulation, etc) predict human efficacious dose.

Who you are:

External website https://jobs.vibrantm.com/merck/job/Darmstadt-Scientific-Director-Discovery-NCE-DMPK-(all-genders)-H


Contact email address: telder@stem-sourcing.com - 21st May 202 [3003]

Director/Senior Director Pharmacometrics Quantitative Pharmacology

Requirements:

External website https://www.stem-sourcing.com


Contact email address: telder@stem-sourcing.com - 18th May 202 [3002]

Clinical Pharmacology Scientist

Be a subject matter expert in clinical pharmacology and work in tandem with quantitative pharmacology on strategy for the direction of the group and compounds in the pipeline. Contribute to regulatory documents e.g. IND's, NDA's and BLA's.

This role requires a PhD with at least 2 years of industry experience. Ability to analyze PK/PD population software such as WinNonlin and NONMEM as well as others.

External website https://www.stem-sourcing.com


Contact email address: broseberry@cartermackay.com - 8th May 202 [3001]

Bay Area CA AD/Director role available in Clinical Pharmacology-full time role with established client. please contact me at broseberry@cartermackay.com for more info. Job Details below: This individual will be responsible for the dual development and implementation of both Clinical Pharmacology and Modeling and Simulation (M&S) strategies in support of the company portfolio.

Professional Responsibilities:

Education/Experience:
Contact email address: cvmopportunities@fda.hhs.gov - 1st May 202 [3000]

Vacancy Announcement
Staff Fellow positions: Clinical Pharmacologist– Division of Scientific Support

The Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), Office of New Animal Drug Evaluation (ONADE), Division of Scientific Support (DSS) is seeking qualified applicants for several Clinical Pharmacologist positions. DSS provides expertise, leadership, and coordination to all CVM offices regarding biostatistics, clinical pharmacology, and environmental safety evaluations for reviews and research. Through our independent and collaborative reviews and evaluations, we support the Center’s scientific and regulatory goals to approve safe and effective animal drugs. This position will be filled through FDA’s Staff Fellowship program. The appointment is up to 2 years with opportunity for renewal.

This position is located on the Clinical Pharmacology Team within the Division of Scientific Support in the Office of New Animal Drug Evaluation (ONADE). The function of the team is to evaluate the absolute and relative bioavailability of a new animal drug/drug product and the pharmacokinetics (absorption, metabolism, distribution, and elimination) of new chemical entities. You will analyze and interpret these scientific investigations, technical data, opinions, and related information, and make recommendations for Agency action regarding New Animal Drug Applications and Investigational New Drug submissions.

Applicants should have experience evaluating study designs, assay methodology, and sensitivity of the assay method of drug products and pharmacokinetics of chemical entities, performing pharmacokinetics & pharmacodynamics modeling and analysis utilizing software such as WinNonLin, NONMEM, or WinBUGS; and developing written summaries of bioavailability, bioequivalence, dissolution and pharmacokinetic studies.

Due to the immensity of its charge, CVM depends upon a diverse and dedicated workforce. We recognize the importance of multi-disciplinary teamwork in reaching superior and timely regulatory decisions therefore we foster an atmosphere where every employee’s contribution is important. New concepts, ideas, and creative approaches to improve current operations and to meet existing and future challenges are encouraged. Our goal is to not only enable our employees to positively impact the Center today, but to prepare our workforce for the demands, responsibilities, and career opportunities of tomorrow. ONADE offers many benefits and operates in a hoteling work environment. Hoteling is an arrangement where employees reserve non-dedicated, non-permanent workspace at the Rockville duty station on an as-needed basis and as required and telework when not at the Rockville duty station. ONADE provides the basic technology (e.g., laptop, monitors, webcam) needed to effectively work in the Rockville office and in a teleworking location. Hoteling, along with a strong telework program and strong electronic communication and workflow tools, affords employees in ONADE the flexibility to balance work/life demands while contributing to our high performing organization.

The position is located in Rockville, Maryland and is available immediately. The salary range for the GS-12 equivalent level is from $86,335 to $112,240, and for the GS-13 equivalent level from $102,663 to $133,465 based on experience and education. Further information regarding qualification requirements can be found at the following link: http://www.opm.gov/policy-data-oversight/classification-qualifications/general-schedule-qualification-standards/0400/pharmacology-series-0405/.

Please submit your letter of interest, resume, and transcripts to: CVMOpportunities@fda.hhs.gov with the subject line of “PharmPK” – Division of Scientific Support Staff Fellow Pharmacologist Position”. Questions may also be directed to the CVM Opportunities mailbox. **Applications will be reviewed and interviews will be scheduled on a first come, first serve basis.**

FDA is an equal opportunity employer and is a smoke-free environment.

External website https://www.fda.gov/about-fda/center-veterinary-medicine/working-cvm


Contact email address: broseberry@cartermackay.com - 15th Apr 202 [2999]

Sr. Director role in clinical pharmacology available in MA. This is a fantastic first in opportunity. please contact me for more info.

Description below.

Position Requirements
Job Requirements:
Contact email address: telder@stemsourcing.com - 9th Apr 202 [2998]

Clinical Pharmacology Lead

Lead all aspects of clinical pharmacology in the Translational Development group of this mid-sized pharma company. Mentor PhD and non-PhD level scientists as well as contribute individually. Use experience in PK/PD, quantitative modeling and simulation, drug development, TK, and nonclinical PK (DMPK and ADME). Provide expertise and guidance for clinical pharmacology plans with minimal supervision.

Qualifications:
PhD with at least 10 years of experience. Experience leading clin pharm programs and being awesome. Experience with PK/PD analysis on INDs, CTDs, NDAs etc. is required for this role. Experience using modeling and simulation software is also a requirement for this role as well as publications reflecting excellence in the field of clin pharm.

For more information on this role reporting to the Vice President of this group.

External website https://www.stem-sourcing.com


Contact email address: broseberry@cartermackay.com - 8th Apr 202 [2997]

New Director/Sr. Director role in Pharmacometrics available. Please email me with questions at broseberry@cartermackay.com

The Director/Sr. Director,will provide strategic and scientific expertise, as well as represent the dept. within the organization. This position will be accountable for developing and applying quantitative frameworks that enable model-informed drug discovery and development across the company portfolio. In addition, this position will ensure robust quantitative data and quality in all deliverables through direct scientific mentorship and management of other QP professionals.

Responsibilities

Experience And Required Skills : Experience
Contact email address: broseberry@cartermackay.com - 3rd Apr 202 [2996]

Discovery/Preclinical PK/PD role in biologics available, east coast US. Job description: (level will be based on experience--ideally someone coming out of a post doc up through mid level)

Experience and Required Skills: :
Requirements
Contact email address: broseberry@cartermackay.com - 31st Mar 202 [2995]

Associate Director, Clinical pharmacokinetics available in southern CA with an established client. please contact broseberry@cartermackay.com for more info

The Clinical Pharmacologist is responsible for providing expertise including, pharmacokinetics (PK), pharmacodynamics (PD) to programs in all stages of development, ranging from pre-New Molecular Entity (NME) declaration through post-marketing support. Will be responsible and accountable for developing compound specific Clinical Pharmacology Development Plan and will apply and promote Clinical Pharmacology knowledge, including that of model-based drug development, in the programs they support for all stages of drug development. Will independently execute the day to day operations for the clinical pharmacology aspects of the assigned programs by managing directly or indirectly teams of employees of different levels.

Key Responsibilities:
Contribute to overall compound development via application of quantitative methods to integrate knowledge of PK, PD, patient characteristics, disease states, and drug—drug interactions to optimize dose selection, dosage regimens and study designs throughout drug development. Will be responsible for appropriate summarization and interpretation of results of PK/PD analyses with respect to their impact on development and clinical use of drugs. Independently or with assistance, clinical pharmacologists will translate quantitative knowledge into strategic opportunities with key stake holders to drive development along the model-based drug development principles.

Education:
PhD, MD, PharmD or equivalent degree in Pharmaceutical Sciences, Clinical Pharmacology, Biomedical Engineering, or relevant Biological Sciences with a minimum of four (4) years of pharmaceutical development experience with at least 3 years of relevant experience performing progressively advanced duties at the Senior Scientist level and 5+ years experience for the Associate Director level.

Experience and Skills:
Demonstrated understanding of overall process of drug development and the overall pharmaceutical R&D process is required.
Has established a strong level of expertise and scientific reputation through multiple publications and presentations, preferred.

External website https://na


Contact email address: jchapman@haallc.com - 26th Mar 202 [2994]

Check out this new opportunity from one of our top clients. Below is a brief description of the role.

Job Description

The Scientist/Director will lead the clinical pharmacology activities on a multi-disciplinary team.

Responsibilities

Job Requirements

If you are interested in learning more, please reach out to me at jchapman@haallc.com.


Contact email address: jchapman@haallc.com - 26th Mar 202 [2993]

Check out this new opportunity from one of our top clients. Below is a brief description of the role.

Job Description

The Sr. Director will lead the clinical pharmacology activities on a multi-disciplinary team.

Responsibilities

Job Requirements

If you are interested in pursuing further, please reach out to me at jchapman@haallc.com!


Contact email address: jchapman@haallc.com - 26th Mar 202 [2992]

Check out this new opportunity from one of our top clients. Below is a brief description of the role.

Job Description The Director will lead the clinical pharmacology activities on a multi-disciplinary team.

Responsibilities
Design and implement clinical pharmacology studies.
Perform model-based analysis of PK/PD and exposure-response data to support dosage selection.
Develop models to evaluate disease progression and trial design performance.
Contribute to the clinical pharmacology sections of trial protocols and reports, brochures, and regulatory submissions.

Job Requirements
Ph.D. in Clinical Pharmacology, Pharmaceutical Sciences, or related field.
8-10+ years of industry experience.
Clinical pharmacology expertise in the oncology therapeutic area.
Experience analyzing PK/PD data using modeling and simulation expertise.
Expertise with modeling tools such as NONMEM, WinNonlin, SAS, and MATLAB.

If you are interested in pursuing further, please reach out!


Contact email address: david.anderson1@takeda.com - 25th Mar 202 [2991]

The DMPK department at Takeda, Cambridge, MA is seeking a highly motivated Scientist to join the Drug Transporter group. The primary responsibilities will include the assessment of NCEs as a potential substrate and inhibitor of drug transporters using various cell-based assays to support projects in early discovery and development stages. A strong understanding of the role of drug transporters in drugs’ ADME and enzyme-transport interplay is critical to this role.

The position level will depend on the level of experience in the relevant areas.

Duties and Responsibilities

  1. Handle and maintain mammalian cell culture,
  2. Conduct cell permeability experiments and in vitro drug transporter studies using various platforms including stably transporter-overexpressed mammalian cells, primary hepatocytes, and membrane vesicles, etc.,
  3. Conduct drug transporter substrate and inhibition assays using radiolabeled and non-radiolabeled probe substrates,
  4. Hands-on experience in operation, maintenance and troubleshooting of HPLC and LC-MS/MS, and
  5. Independently design and execute experiments, analyze, critically interpret and document data in reports
Qualifications

External website https://takeda.wd3.myworkdayjobs.com/External/job/Boston-MA/Associate-Scientist---Scientist-I---Drug


Contact email address: amir.youssef@synteract.com - 20th Mar 202 [2990]

An Associate Director, Pharmacokinetics position is open at Synteract. The position can be office-based or remote-based in the US.

Who We Are
Synteract is a global full-service contract research organization with a successful three-decade track record supporting biotechnology, medical device and pharmaceutical companies. With our mission of ”Bringing Clinical Trials to Life,” we provide customized Phase I through IV services internationally, offering expertise across multiple therapeutic areas including notable depth in Oncology, Neuro Degenerative Diseases, and Rare and Orphan Diseases, and in pediatric populations. Our mission is to support the innovation and development of better therapies in healthcare.

Position Overview
The Associate Director, Pharmacokinetics will be responsible for conducting PK/PD modeling and population PK analyses using WinNonlin, NONMEM and/or PKSim with a focus on designing optimal dosing regimens for adult, pediatric and other special patient populations. Provide pharmacology, pharmacokinetic consulting to clients with a specialization on pediatric patient populations. Design, analyze and report pre-clinical and clinical pharmacokinetic, PK/PD modeling and trial simulation studies.

Specific tasks would include:

Qualifications: If you’re passionate about bringing clinical trials to life, we encourage you to apply today!

Synteract’s policy is to provide equal employment opportunity and affirmative action in all of its employment practices without regard to race, color, religion, sex, national origin, ancestry, marital status, protected veteran status, age, individuals with disabilities, sexual orientation or gender identity or expression or any other legally protected category. Applicants for positions with Synteract must be legally authorized to work in the country which they are applying, and verification of employment eligibility will be required as a condition of hire.

Please apply at https://www.synteract.com/Careers/Career-Opportunities

External website https://www.synteract.com/Careers/Career-Opportunities


Contact email address: telder@stem-sourcing.com - 17th Mar 202 [2987]

The Clinical Pharmacology Leader is a highly scientific role, supporting study design, PK and PK/PD analyses, and overall drug development support. The candidate will have an excellent knowledge of Clinical Pharmacology principles, such as PK, PK/PD, drug metabolism, and DDI, as well as a good understanding of related disciplines such as pharmaceutical development, regulatory, and overall drug development.

Key Responsibilities:

Minimum Qualifications :

External website https://www.stem-sourcing.com


Contact email address: lienqu@pcom.edu - 3rd Mar 202 [2986]

PCOM School of Pharmacy is currently seeking a qualified individual for one full-time, Assistant / Associate Professor, tenure-track faculty position in the Department of Pharmaceutical Sciences specializing in pharmacokinetics, pharmacology, and/or biopharmaceutics/pharmaceutics. The job location is at PCOM Georgia in Suwanee, GA (metro Atlanta area).

Essential Duties and Responsibilities Duties and responsibilities include (but are not limited to) the following:

​Teach in the Doctor of Pharmacy curriculum on topics related to pharmacokinetics, pharmaceutics, and dosage forms along with other areas of pharmaceutical sciences as part of a team-taught curriculum.

Develop and maintain an extramurally funded research program and participate in a collaborative, interdisciplinary research environment with other faculty in the school of pharmacy.

Contribute to the service needs of the school, participating on school and college-wide committees, and in student advising.

Other duties as assigned.
Education: A Ph.D. in Pharmacokinetics/ Pharmaceutical Sciences / Pharmaceutics or a closely related discipline required. A B.S. degree in pharmacy or PharmD. is preferred but not required.

Experience: 2 years of postdoctoral training or teaching experience
Desirable qualifications at the Assistant Professor level include: Postdoctoral experience in pharmacokinetics. Prior academic teaching experience. Successful record of peer-reviewed publications in pharmacokinetics. Evidence of an ability to establish an extramurally funded research program.
Desirable qualifications at the Associate Professor level include: Prior teaching experience at the Assistant Professor level in a School of Pharmacy. Proven record of scholarship in pharmacokinetics. Establishment of independent extramurally funded research program.

All inquiries MUST include:
A letter of intent Teaching and research philosophy A curriculum vitae Salary requirements Three (3) references, preferably from current or former supervisors.

External website https://www.pcom.edu/about/departments/human-resources/career-opportunities/


Contact email address: david.anderson1@Takeda.com - 24th Feb 202 [2985]

Job Description

The DMPK department at Takeda, Cambridge, MA is seeking a highly motivated Scientist to join the Drug Metabolism group. The primary responsibilities will be profiling and characterization of metabolites (small molecules)/catabolites (ADCs, proteins, and peptides) from complex biological matrices. A strong background in delineating biotransformation pathways and structural elucidation by LC-MS is required. A successful candidate must exhibit strong communication and interpersonal skills and desire to work in a fast-paced, flexible and dynamic environment. Experience with in vivo preclinical and clinical ADME studies and understanding of clearance route, mechanism and the role of metabolism/catabolism is essential.

External website https://http://bit.ly/Takeda_DMPK


9th Feb 202 [2984]

Postdoctoral Fellowship in Pharmacokinetics/Pharmacodynamics

UNC Eshelman School of Pharmacy University of North Carolina at Chapel Hill

A postdoctoral research associate position is available to work on a project focused on characterizing the pharmacokinetics of drugs in children with obesity. The project will involve the use of physiologically-based pharmacokinetic (PBPK) and population pharmacokinetic (PopPK) modeling techniques to identify optimal drug dosing for children with obesity.

Educational requirements: PharmD, MD, or PhD with knowledge of pharmacokinetic/pharmacodynamic analyses.

Qualifications and experience: demonstrated software proficiency (e.g., PK-Sim®, NONMEM®, R) is preferred. Excellent communication skills and ability to work independently as well as a member of an interdisciplinary team are essential.

The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.

External website https://unc.peopleadmin.com/postings/176772


Contact email address: matt_laughon@med.unc.edu - 7th Feb 202 [2983]

The Division of Neonatal-Perinatal Medicine at UNC - Chapel Hill is recruiting for a fixed-term, full time faculty position. This position will provide support in the design and preparation of clinical pharmacokinetics development strategies and study protocols, perform pharmacokinetic (PK) and pharmacodynamics (PD) analyses, prepare clinical study reports and integrate summary documents. This position will also conduct and coordinate the PK/PD analysis and statistical effort for clinical trials at all stages of drug development.

Educational requirements: PharmD, MD, or PhD in pharmaceutical sciences or pharmacology.

Qualifications and Experience: Candidate should be proficient in PK/PD or related analyses and extensive knowledge of Winnonlin and NONMEM software required. Demonstrate technical expertise of clinical trial simulations and pediatric drug development. Knowledge of clinical database, PK/PD compilation and manipulation with scripting software of SAS, STATA.


Contact email address: telder@stem-sourcing.com - 4th Feb 202 [2982]

Director of Quantitative Pharmacology

The Director will combine strong pharmacometric skills with a deep biological understanding. They are responsible for independently determining, planning, and executing M&S analyses for an entire drug development program in close collaboration with cross-functional colleagues within the R&D organization. Specific experience and interest in working in population PK/PD or quantitative systems pharmacology is required. The Director determines, plans, and executes technically challenging analyses by using state of the art Modeling & Simulation methodologies to strongly contribute to critical decision making. The Director will lead M&S projects for an entire drug development program to evaluate study design, dose selection, probability of success estimation, portfolio strategy, pediatric extrapolation etc. In this role, it is expected that they will represent M&S with cross-functional drug development teams, proactively advocate for model-based approaches, and clearly communicate M&S results.

KEY RESPONSIBILITIES:

PREFERRED EDUCATION AND EXPERIENCE:

External website https://www.stem-sourcing.com


Last update: Thu 30 Jul 2020 10:53:31 pm


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