PK/PD and Other Jobs

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Contact email address: anna.sher@pfizer.com - 21st Feb 2018 [2870]

Application call for a postdoctoral fellowship position at Pfizer, Cambridge, USA
Postdoctoral Fellow, Systems Modeling The Quantitative Systems Pharmacology (QSP) Lab in Pfizer’s Internal Medicine Research Unit (IMRU) is responsible for developing insights to help advance IMRU clinical candidates; identifying and evaluating promising new therapeutic targets through physiologically-based modeling and simulation; and analysis and interpretation of preclinical and clinical data. We seek a highly motivated postdoctoral candidate to develop and analyze mechanistic, mathematical models of cardiac and skeletal muscle mitochondria metabolism to enable the in silico testing of mechanistic hypotheses of metabolic inflexibility with the ultimate goal of improving the identification and evaluation of therapeutic targets for heart failure (HF) and type 2 diabetes mellitus (T2DM). Please visit the following link for more information: https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---Massachusetts---Cambridge/Postdoctoral-Fellow--Systems-Modeling_4692921 Starting date: March 2018 (negotiable)

If interested, please apply via the above link or contact anna.sher@pfizer.com

External website http://https://pfizer.wd1.myworkdayjobs.com/PfizerCareers/job/United-States---Massachusetts---Cambridge/Pos


21st Feb 2018 [2869]

Postdoctoral Fellowship in Pharmacokinetics/Pharmacodynamics

UNC Eshelman School of Pharmacy University of North Carolina at Chapel Hill

A postdoctoral research position is available immediately to work on projects focused on characterizing the pharmacokinetic/pharmacodynamic properties of drugs used in the pediatric population. The projects will involve use of nonlinear mixed effects and physiologically based pharmacokinetic modeling techniques to identify optimal pediatric dosing and clinical trial design. Requirements: minimum of a PharmD, MD, or PhD with knowledge of PK/PD analyses.

Preferred experience: demonstrated software proficiency, including NONMEM and R or SAS, is preferred. Previous experience in performing in vitro drug metabolism or transporter studies is also preferred. Excellent communication skills and ability to work independently as well as a member of an interdisciplinary team are essential.

Interested applicants should submit a letter describing personal goals as they relate to the position, Curriculum Vitae, and 3 professional references at http://unc.peopleadmin.com/postings/134532

The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.

External website https://unc.peopleadmin.com/postings/134532


Contact email address: basiler2@gene.com - 5th Feb 2018 [2868]

Temp/Contractor Job Description (available 3-yr contract):

Position: Scientific Researcher(SR)/Senior Scientific Researcher(SSR)– Mass Spectrometry

Department: Assay Development & Technology (ADT), BioAnalytical Sciences (BAS)

Description:
In the BioAnalytical Sciences (BAS) Department at Genentech, we are a world-class bioanalytical center of excellence for novel strategies, technologies, and methods that enable the development of life-changing medicines. We do this by fostering an innovative and collaborative environment that values and recognizes a diversity of contributions.

The BAS/Assay Development and Technology (ADT) department is seeking a highly motivated Scientific Researcher (SR) / Senior Scientific Researcher (SSR) contractor to support antibody, antibody-drug conjugate (ADC) and other complex biotherapeutic projects in research and development. Responsibilities of this laboratory-based position will include quantification of recombinant therapeutic proteins, unconjugated drug and conjugated drug levels for ADCs and characterization of structural changes in these biotherapeutics, in biological matrices using LC-MS, and other analytical techniques. This individual will explore immuno-capture and mass spectrometry-based methods to support assessment of pharmacokinetics, and biotransformations of therapeutic antibodies, ADCs and other complex molecules in preclinical and clinical studies. This individual may also be involved in non-GLP sample analysis and data reporting. The individual will work independently and in collaboration with colleagues within BAS/ADT and across various functional areas. He or she may also be involved in evaluating and exploring innovative technologies.

Skills: In-depth knowledge and hands-on experience in HPLC and mass spectrometry with a proven track record of solving bioanalytical problems. Experience in quantitative LC-MS-MS method development is required. Expertise in bioanalysis of therapeutic proteins or proteomics is highly desirable. Specific hands-on experience with QTRAP 5500-6500, TripleTOF 5600-6600, and/or Orbitrap mass spectrometer technologies is a plus. The individual should be a motivated team player with excellent oral and written communication skills

Education/Experience:
A BS or MS degree in Analytical Chemistry, Biochemistry or a related scientific discipline with specialization in mass spectrometry required. Industry experience in pharmaceutical or biotechnology drug development for 2-5 years preferred.


Contact email address: rrais2@jhmi.edu - 29th Jan 2018 [2867]

The Johns Hopkins Drug Discovery (JHDD) team is seeking a skilled and motivated researcher with experience in Drug Metabolism and Pharmacokinetics.  The program is multidisciplinary and focused on the discovery and development of novel small molecule drugs in the areas of Neurology, Oncology, Gastroenterology, Ophthalmology, and Immunology. The individual selected will be responsible for analytical method development (MS/MS), pharmacokinetic analyses, drug permeability analyses, drug metabolism (liver microsomes, S9, hepatocytes, etc.), and protein binding studies. In addition, he/she will be expected to also understand the absorption, distribution and elimination principles for application to the characterization of internal drug candidates.

JHDD will provide a dynamic research environment including interactions with JHU faculty, medicinal chemists, biochemists, cell biologists and in vivo pharmacologists, as well as interaction with several Pharma industrial partners.

Requirements for the position include:
A bachelor or masters degree in biology, pharmacology, pharmaceutical sciences or related field
Knowledge of in vitro techniques, cell culture, LC/MS and pharmacokinetics is desirable
Ability to perform effectively in a team environment
Good oral communication and writing skills

Located in the new Biotechnology Park, Johns Hopkins Drug Discovery Program was created with the mission of identifying novel drug targets arising from JHU faculty’s research and translating them into new drug therapies for neurological disorders.

The integrated staff has expertise in medicinal chemistry, assay development, animal pharmacology/toxicology, drug metabolism and pharmacokinetics, and the knowledge necessary to bring novel drugs to the clinic.

External website http://https://drugdiscovery.jhu.edu/


Contact email address: a252919951@163.com - 6th Jan 2018 [2866]

We are currently hiring some Pharmacometrics and Clinical Pharmacology positions for some leading global/local/start-up companies. Based in Shanghai/Beijing, China.

Pharmacometrics Position for a Leading Global company Title can be Principal Scientist/Sr. Principal Scientist. Qualification:

PhD degree or above with 8 years industry experience; Experience with Modeling&Simulation software(e.g. NONMEN Monolix Phoenix) Good knowledge of clinical pharmacology and development processes. Clinical Pharmacology Head Position for a Local Pharma Qualification: PhD degree or above with 12 years experience Candidate must have experience both in Clinical Pharmacology and Pharmacometrics Fluent in Chinese and English Clinical Pharmacology Head Position for a Start-up Company Qualification: PhD degree or above with 12 years experience Rich experience in Pharmacometrics and Clinical Pharmacology If you are interested in this kind of position. Please feel to contact me.

External website http://www.af-recruiting.com


Contact email address: sylvia.zhao@novartis.com - 6th Jan 2018 [2865]

The Novartis Institutes for BioMedical Research (NIBR) is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients. NIBR includes about 6500 associates across 7 locations worldwide. Translational Medicine (TM) is the clinical research arm of NIBR, and includes about 1000 associates globally. TM plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, and bridging drug discovery and clinical application. PK Sciences (PKS) partners across both NIBR and the Global Drug Development organizations to advance the scientific knowledge of pharmacokinetics, metabolism and clinical pharmacology, and bring it to bear on drug discovery and development challenges throughout R&D.

We are currently seeking a senior Clinical Pharmacologist or DMPK expert (Investigator III) to join our team. The position will be based in Shanghai, China, and will report to the Director of PK Sciences, China Site Head.

Core Responsibilities: Lead the PK Sciences strategy (preclinical DMPK and clinical pharmacology) and influences project strategy for discovery, translational, development or lifecycle management programs in China.

  1. Represents PK Sciences as a core member of discovery, translational medicine, full development and/or lifecycle management project teams. Responsible for the timely and effective communication of data, strategy and results to the project teams
  2. Aligns plans and strategies with sub-teams, project teams, manager and leadership team.
  3. Analyzes and interprets PK/TK/PD/IG data generated during discovery, early and/or full development; present results to the program.
  4. Co-authors and prepares key preclinical and clinical, and regulatory documents including, but not limited to: clinical study protocols, clinical study reports, modeling reports, investigator brochures, IND/IMPDs and NDAs within agreed timelines, and meeting all regulatory requirements.
Professional Requirements:
  1. PhD/Pharm.D. level scientist with relevant experience in drug metabolism and pharmacokinetics or related back ground
  2. 6+ years of experience in drug discovery, development or a relevant environment (e.g., Drug Metabolism and Pharmacokinetics).
  3. Proven knowledge of PK Sciences (Clinical Pharmacology, PK/PD, DMPK) experience in working in project teams and knowledge of regulatory requirements.
  4. Demonstrated success in working cross functional team in a highly dynamic, matrixed, project-team environment.
  5. Strong organizational and project skills with critical thinking and problem solving skills.
  6. Strong oral and written communication skills.
  7. Experience in global programs or multinational companies is a plus
How to apply: Please forward your CV (in English) by email to Sylvia Zhao, Director PK Sciences – sylvia.zhao@novartis.com
Contact email address: liane.brown.feaheny@vennlife.com - 6th Dec 2017 [2862]

Venn Life Sciences is an Integrated Drug Development Partner offering a unique combination of drug development expertise and clinical trial design and management. This enables us to create, plan and execute drug and medical device development programs effectively and seamlessly for our clients. We have dedicated operations in Ireland, France, Germany, the Netherlands, the UK, the US, and European-wide representation.

Our vision is to deliver results of the highest quality to our global sponsors on time and within budget. We do this through developing our staff to be world class in their fields and forming real, lasting relationships with our clients.

Our Early Development Services Division is a leading partner in early drug development seamlessly integrating chemistry manufacturing and control, non-clinical development, early clinical development, regulatory affairs, quality assurance and project management.

We are currently seeking a Senior Clinical Pharmacologist to join our team. The position will be based in Breda, Netherlands and will report to the Director of Clinical Development.

Specialising in early drug development, up to proof of concept, our Clinical Development Department provides clinical consultancy for drug development and clinical operations (medical writing, clinical trial management, pharmacovigilance). In addition, Clinical Development closely collaborate with our Clinical Pharmacokinetics, Pharmacometrics and Biometrics (PKPB) Department and with other departments of Venn Life Sciences.

Role:
The Senior Clinical Pharmacologist will:

The successful candidate will have: The position will be offered for a minimum of 32 hours per week, initially a one-year contract will be offered with the option to extend to a permanent contract.

How to apply:
Please forward your CV (in English) and motivation letter by email to Liane Brown-Feaheny, HR Generalist - liane.brown.feaheny@vennlife.com

If you would like more information regarding this position or for a confidential discussion regarding your career please send an e-mail to Katsuhiro.Mihara@vennlife.com, Director Clinical Development.

We do not require the services of agencies for this role.

PLEASE NOTE THAT DUE TO THE HIGH VOLUME OF APPLICATIONS WHICH WE RECEIVE WE WILL ONLY BE ABLE TO REPLY TO CANDIDATES WHOM WE ARE INVITING FOR INTERVIEW

External website http://www.vennlifesciences.com/


4th Dec 2017 [2861]

The Division of Clinical Pharmacology V, Office of Clinical Pharmacology at FDA is recruiting clinical pharmacologists. The focus of our division is the development and regulatory evaluation of:

Interested candidates can submit Curriculum Vitae to Dr. Brian Booth ( brian.booth@fda.hhs.gov).
For information about Office of Clinical Pharmacology at FDA, please visit our website at https://www.fda.gov/aboutfda/centersoffices/officeofmedicalproductsandtobacco/cder/ucm106189.htm
Contact email address: liane.brown.feaheny@vennlife.com - 4th Dec 2017 [2860]

Consultant Pharmacometrician - Venn Life Sciences

Venn Life Sciences is an Integrated Drug Development Partner offering a unique combination of drug development expertise and clinical trial design and management. This enables us to create, plan and execute drug and medical device development programs effectively and seamlessly for our clients. We have dedicated operations in Ireland, France, Germany, the Netherlands, the UK, the US, and European-wide representation.

Our vision is to deliver results of the highest quality to our global sponsors on time and within budget. We do this through developing our staff to be world class in their fields and forming real, lasting relationships with our clients.

Our Early Development Services Division is a leading partner in early drug development seamlessly integrating chemistry manufacturing and control, non-clinical development, early clinical development, regulatory affairs, quality assurance and project management.

We are currently looking for an experienced Consultant Pharmacometrician to join our team. The position will be based in Breda, Netherlands and will report to the Director Clinical Pharmacokinetics, Pharmacometrics and Biometrics (PKPB).

If you are seeking a rewarding and challenging career this could be the perfect opportunity for you.

Your Role:
The Consultant Pharmacometrician will have the following key tasks:

Your Profile
The successful candidate will have: The position will be offered for a minimum of 32 hours per week, initially a one-year contract will be offered with the option to extend to a permanent contract.

How to apply: Please forward your CV (in English) and motivation letter by email to Liane Brown-Feaheny, Human Resources Generalist, via liane.brown.feaheny@vennlife.com.

If you would like more information regarding this position or for a confidential discussion regarding your career please send an e-mail to Katsuhiro.Mihara@vennlife.com, Director Clinical Development.

We do not require the services of agencies for this role.

PLEASE NOTE THAT DUE TO THE HIGH VOLUME OF APPLICATIONS WHICH WE RECEIVE WE WILL ONLY BE ABLE TO REPLY TO CANDIDATES WHOM WE ARE INVITING FOR INTERVIEW.

External website http://www.vennlifesciences.com/


Contact email address: mehvar@chapman.edu - 27th Nov 2017 [2859]

A Post-doctoral Position is available in the Department of Biomedical & Pharmaceutical Sciences at Chapman University School of Pharmacy in Irvine, California. The specific research includes the use of animal models to study the effects of liver diseases on the transporter- and/or cytochrome P450-mediated hepatobiliary and brain disposition of drugs. Candidates with a Ph.D. degree in Pharmaceutical Sciences with interest in the areas of pharmacology/ pharmacokinetics/drug disposition/drug metabolism will be considered. Additionally, the position requires prior experience with surgical procedures in rodents and analytical methods, such as LC/MS/MS, demonstrated by strong peer-reviewed publications. Excellent oral and written communication skills and ability to work independently or as part of an interdisciplinary team are essential. The successful candidate will work in a new research facility, which is equipped with the state-of-the-art research equipment.

Qualified applicants should submit a curriculum vitae, summary of research interests, and names/titles and contact information of three references electronically to Dr. Reza Mehvar (mehvar@chapman.edu). Review of applications starts immediately and will continue until the position is filled. The position is available on January 1, 2018.

Chapman University is an Equal Opportunity Employer, committed to providing career opportunities to all people, without regard to race, color, religion, sex, age, national origin, sexual orientation, disability, or veteran status.


Contact email address: sam.huang@af-recruiting.com - 16th Nov 2017 [2858]

Pharmacometrics/Clinical Pharmacology Positions

We are currently hiring some Pharmacometrics and Clinical Pharmacology positions for some leading global/local/start-up companies. Based in Shanghai/Beijing, China.

Pharmacometrics Position for a Leading Global company Title can be Principal Scientist/Sr. Principal Scientist.
Qualification:

  1. PhD degree or above with 8 years industry experience;
  2. Experience with Modeling&Simulation software(e.g. NONMEN Monolix Phoenix)
  3. Good knowledge of clinical pharmacology and development processes.
Clinical Pharmacology Head Position for a Local Pharma
Qualification:
  1. PhD degree or above with 12 years experience
  2. Candidate must have experience both in Clinical Pharmacology and Pharmacometrics
  3. Fluent in Chinese and English
Clinical Pharmacology Head Position for a Start-up Company
Qualification:
  1. PhD degree or above with 12 years experience
  2. Rich experience in Pharmacometrics and Clinical Pharmacology
If you are interested in this kind of position. Please feel to contact me.

External website http://www.af-recruiting.com


Contact email address: jchapman@haallc.com - 12th Oct 2017 [2856]

Clinical Pharmacology Consultant

Job Description Experienced leader with strong clinical pharmacology experience.

Responsibilities Represent the clinical pharmacology project team. Design and implement strategies and plans for the team. Analyze PK/PD data and drug-drug interactions to advise dosage selection. Collaborate with external partners to ensure adequate project progression.

Job Requirements Ph.D. in Pharmaceutical Sciences or related field. 5+ years of industry experience. Clinical pharmacology expertise. Hands-on experience with modeling and simulation software.

External website http://haallc.com/compas/?cjobid=AW504961012&rpid=106412


12th Oct 2017 [2855]

About Idorsia Pharmaceuticals Ltd
Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients. In order to achieve this we will develop Idorsia into one of Europe's leading biopharmaceutical companies, with a strong scientific core. Headquartered in Switzerland - a European biotech hub - Idorsia is specialized in the discovery and development of small molecules, to transform the horizon of therapeutic options. Idorsia has a broad portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center, and a strong balance sheet – the ideal constellation to bringing R&D efforts to business success. Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017 and has over 600 highly qualified specialists dedicated to realizing our ambitious targets.

In our Nonclinical Pharmacokinetics and Metabolism Department (DMPK) we are seeking an Experimental Nonclinical Pharmacokineticist (Job ID: DD1731)

Job Responsibilities

What Idorsia offers Data Privacy By applying you signify you have read and agreed our Data Privacy Policy which is available on our WebSite at the following page: https://www.idorsia.com/careers/faq/privacy-policy

Work Location: Allschwil near Basel Country: Switzerland Business Area: Preclinical Development Schedule: Fulltime Job Type: Permanent

If you are interested, please send your CV and motivation letter by email to idorsia.careers@idorsia.com clearly stating the job title and reference of the position to which you are applying in the subject line. Please be informed that if you are selected for this position, your employment will be subject to a preemployment background screening process, of which you would be informed in greater detail in due course.

External website https://www.idorsia.com/careers/job-opportunities


Contact email address: yjeong@uic.edu - 30th Sep 2017 [2854]

Postdoctoral researcher position:

The Department of Pharmacy Practice at the University of Illinois at Chicago is seeking a postdoctoral research associate (or a research specialist) to work on a collaborative clinical project involving pharmacokinetic analysis. A PhD degree in pharmacokinetics, analytical chemistry, or other relevant areas is required. The candidate will mainly analyze biological samples for quantitation of small molecules using LC-MS/MS. Additionally, s/he will have to perform preclinical in vitro DMPK assays. For information about the lab, please visit http://openwetware.org/wiki/Jeong_lab. For fullest consideration, applicants should send a CV and three references by October 31, 2017 to: Young Jeong at yjeong@uic.edu.

External website http://openwetware.org/wiki/Jeong_lab


Contact email address: msnow@ribontx.com - 27th Sep 2017 [2853]

Associate Director, DMPK

Ribon Therapeutics is a biotechnology company pioneering the discovery of new cancer medicines that target monoPARP proteins, critical regulators of cancer survival mechanisms. Ribon offers a fast-paced, team-oriented work environment and a comprehensive benefits package, including health, dental, 401(k), paid vacation, and much more. Ribon is located in Lexington, Massachusetts.

JOB SUMMARY
The candidate will be an integral member of a team responsible for discovering and developing transformative cancer medicines that target cellular stress pathways. This position reports to the Vice President of Molecular Discovery and the individual will be responsible for:

JOB REQUIREMENTS

External website http://www.ribontx.com/2017/06/14/associate-director-dmpk/


Contact email address: sam.huang@af-recruiting.com - 14th Sep 2017 [2852]

Chinese Opportunity:

Now we are working on some Clinical Pharmacology positions for global/local/Startup CRO. Based in Shanghai/Beijing.

Local Pharma Base:Beijing Position:Head of Clinical Pharmacology
Minimum Qualifications / Experiences:

  1. PhD or MD or equivalent degrees, generally 8 years of pharmaceutical development experience.
  2. Broad clinical pharmacology experience and M&S experience is required.
  3. Experience in the use of scientifc software for modelling, simulation or programming (such as SAS, NONMEM, R or S-plus)
  4. Fluent in written and spoken English
  5. Excellent written and oral communication skills and able to communicate effectively with individuals and groups in the organization (communication)
Responsibility:
  1. Build Clinical Pharmacology team.
  2. Responsible for designing, developing and implementing clinical pharmacology plans and strategies for supporting end-to-end projects
  3. Set PK and PK/PD strategies and overall clinical pharmacology characterization strategies for compounds under drug development for global regulatory submission
  4. Work with other departments
Leading CRO Base:Shanghai Position:Head of Clinical Pharmacology
Minimum Qualifications / Experiences:
  1. PhD or MD or equivalent degrees, generally 5 years of pharmaceutical development experience.
  2. Broad clinical pharmacology experience and M&S experience is required.
  3. Strong knowledge and experience in either oncology, immunology, tumor immunology, infectious disease, and/or ophthalmology are highly desired.
  4. Strong knowledge and experience in PK and PK/PD of large molecule therapeutics (e.g., monoclonal antibodies, bispecifics, fusion proteins, antibody-drug conjugates, etc.) are highly desired. Working knowledge of PK/PD software (e.g., WinNonlin, NONMEM, ADAPT II) and the ability to critically assess PK/PD data is necessary.
  5. The candidate should have experience working on cross-functional teams, demonstrate excellent communication skills, and have the ability to work independently and effectively.
Global Pharma Position:Manager/Senior Manager/Associate Director
Minimum Qualifications / Experiences:
  1. PhD or MD or equivalent degrees.
  2. Strong knowledge of PK/PD.
  3. Fluent in written and spoken both English and Chinese.

External website http://www.af-recruiting.com/


Contact email address: recruitment@model-a.com.au - 11th Sep 2017 [2851]

Pharmacometrician / Senior Pharmacometrician Positions Brisbane, Australia

The Position
Model Answers Pty Ltd is seeking applications for a pharmacometrician / senior pharmacometrician to join their team in Brisbane, Australia. The successful candidate(s) will work in an inspiring group that provides a range of quantitative solutions to a global client network. The positions are suited to highly motivated individuals who are looking for a challenging opportunity to facilitate successful drug development. Applicants should have excellent time management and communication skills, and have a background in pharmacokinetic / pharmacodynamic data analysis. Applicants should also have a strong programming background in R or SPlus, and demonstrated modelling experience using NONMEM / BUGS or equivalent software.

The Location
All positions are located in the central business district of Brisbane, Australia, which has a beautiful subtropical climate, a strong economy, and low levels of unemployment. Model Answers Pty Ltd is a growing consultancy business dedicated to helping pharmaceutical and biotech companies make successful drug development decisions. Employees, shareholders and equity stake holders are expected to be upstanding members of the community, who have an inbuilt desire to develop, create, and innovate. Opinions and ideas are welcomed, resulting in a dynamic business, led by those who work in the business.

Interested applicants should contact Bruce Green at recruitment@model-a.com.au or refer to the website (www.model-a.com.au) for further information.


Contact email address: noelle.williams@utsouthwestern.edu - 8th Sep 2017 [2850]

The Preclinical Pharmacology Core (PPC) and the Department of Biochemistry at UT Southwestern Medical Center (Dallas, TX) seek a motivated staff associate to work in the Core. The PPC (http://www.utsouthwestern.edu/labs/preclinical-pharmacology-core/) provides expertise in bioanalytical method development, drug metabolism, pharmacokinetics and early animal toxicity and efficacy studies to the UTSW community and other area institutions for drug discovery and development projects. The new hire will be responsible for conducting both in-vitro and in-vivo experiments to support these activities. Ideally, candidates should be experienced in the handling of animals (rats and mice) and have some cell culture experience. Exposure to LC-MS/MS and in vitro drug metabolism or other preclinical pharmacological assays (protein binding, solubility determination, CACO2 bidirectional efflux assays) is highly desirable.

It is anticipated that the successful candidate will be able to design, execute and interpret the in-vitro and in-vivo assays to support the drug discovery and development initiatives with some training. Past associates have been well-published during their tenure in the PPC.

Minimum Requirements: B.S. with 3-5 years of experience in animal work and/or analytical assays or Ph.D. in Pharmacokinetics & Metabolism, Pharmacy, Biological Sciences or related field. Applicants should have excellent communication and problem-solving skills and a strong work ethic. For further information or to apply, see: https://jobs.utsouthwestern.edu/job/sr-research-associate-biochemistry-research-laboratory-5323-harry-hines-blvd-da-11549/ or contact Dr. Noelle Williams (Noelle.williams@utsouthwestern.edu).


Contact email address: gobeaun@mmv.org - 1st Sep 2017 [2849]

PKPD Translational Medicine Scientist (3 years' post-doc fellowship)

Deadline: Saturday, 30 September 2017

Location: Geneva, Switzerland

MMV is a leading product development partnership (PDP) in the field of antimalarial drug research and development. Its mission is to reduce the burden of malaria in disease-endemic countries by discovering, developing and delivering new, effective and affordable antimalarial drugs.

Over the past 17 years, MMV has worked with an extensive network of donors, private and public sector partners, experts and clinical centres in endemic countries to develop an outstanding portfolio of antimalarial projects.

However, malaria parasites resistant to artemisinin and its partner drugs have emerged making the need to develop new combinations more urgent. MMV and its partners are successfully developing new antimalarial compounds and are at the stage of selecting combinations among these for further development. Thus we are seeking a PKPD Translational Medicine Scientist to join our team for a 3-year period to help identify the most promising combinations by translating the PKPD from animals to humans.

This 3-year post-doctoral fellowship will provide a PhD graduate with the opportunity to expand their scientific knowledge and skills. Working under the direct supervision of a senior pharmacometrician, the successful candidate will have the opportunity to see how pharmacometric approaches (PBPK and PK/PD modeling and simulation) are used to speed up the drug development process, from early to late stage. They will also contribute to the development of innovative modeling approaches to help the interpretation of in vitro data, the translation from preclinical to clinical, and dose selection for clinical studies. Following this experience, the fellow will be well-equipped to accept opportunities in academia, industry or other R&D product development partnership organizations.

The PKPD Translational Medicine Scientist will:

Education and experience:

Technical skills required:

Behavioural skills required:

Preference will be given to Swiss citizens and candidates who hold a valid work permit.

Interested applicants should send their CV and a cover letter giving reasons for their interest in the position to jobs@mmv.org(link sends e-mail) before 30 September 2017. Please refer to the following code in the subject line of your email: RD-2017-15.

Recruitment agencies are kindly requested to refrain from submitting applications.

External website http://https://www.mmv.org/about-us/jobs/pkpd-translational-medicine-scientist-post-doc-fellowship


Last update: Wed 21 Feb 2018 12:16:40 pm


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