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Hi All,
Anybody have any experience with liver enzyme induction (ALT, AST,
ALP, any of the p450's) following Ketamine sedation in rhesus or
cynomolgus macaques? I plan on sedating them with 5-20 mg/kg
Ketamine followed by administration of the test product.
Also, does anyone know of any class of drugs that could interact with Ketamine?
Thanks for the help in advance.
Cheers!
Pano M. Xinos
Study Director/Toxicologist
LAB Pre-Clinical Research International Inc.
O: (450) 973-2240 x216
F: (450) 973-2259
C: (514) 821-3705
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Hi there,
CNS depressants can enhance the hypotensive effect of ketamine
(barbiturates, alpha-blocking agents, etc.).
Richard Molitor, R.Ph.
http://www.angelfire.com/wa/pharmacist/
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Copyright 1995-2010 David W. A. Bourne (david@boomer.org)