PharmPK Discussion - Red blood cell penetration

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On 5 Sep 2000 at 11:12:04, Alexander.Treiber.at.Actelion.Com sent the message


Are there assays that allow measuring penetration of drugs INTO red
blood cells which also allow for differentiating between the former
and binding of drugs onto the surface of RBCs. What physicochemical
parameters of a molecule would have to be optimized if one wants to
push compounds into RBCs?

Thanks for your help
Alex

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