PharmPK Discussion - Statins in saliva

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On 28 Mar 2000 at 22:30:46, Thierry Buclin (Thierry.Buclin.aaa.chuv.hospvd.ch) sent the message


Dear PharmPK users,

Has anybody some experience of the determination of HMG-CoA reductase
inhibitors (statins) in saliva ? I am seeking for methodological
advice and preliminary data, to design a clinical trial using saliva
for non-invasive PK sampling.
Thanks in advance

   Thierry BUCLIN, MD
   Division of Clinical Pharmacology
   University Hospital CHUV - Beaumont 633
   CH 1011 Lausanne  -  SWITZERLAND
   Tel: +41 21 314 42 61 - Fax: +41 21 314 42 66

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