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Dear All,
How can i get population pharmacokinetics sample data for NONMEM practice. If such data base is
available some where, please let me know.
Regards,
Abhisheak Sharma,
Research Fellow
Pharmacokinetics & Metabolism Division,
Central Drug Research Institute, Lucknow (UP)
[Boomer (http://www.boomer.org) can generate random practice data using the multiple random
simulation option. The NONMEM website may have some?? - db]
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Hi Abhisheak,
NONMEM provides you with some example datasets typically it will be in your NONMEM installation
folder.
The folder contains example datasets, ctl files and output files as well.
Hope this helps.
Thanks,
Soujanya
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Dear Abhisheak,
There are also good datasets associated with the nonmem case study material on the ACCP
pharmacometrics resource. You can follow the three case studies here:
http://accp1.org/pharmacometrics/cs.htm
The material is slightly dated (comes from nonmem version 5 and uses older S-plus code for the
plotting) however the dataset and concepts are still quite useful and relevant.
Best of luck!
Devin Pastoor
Research Scientist
Center for Translational Medicine
University of Maryland, Baltimore
www.ctm.umaryland.edu
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The ACCP website has some nice practice datasets and codes.
http://accp1.org/pharmacometrics/modeling.htm
Good Luck
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Abhisheak,
Devin already pointed you to the ACCP tutorials; to help visualise the problems better I put
together a Phoenix workflow that uses their NONMEM code launched through Phoenix as well as some R
scripts etc.
There is also the same model in NLME to compare and contrast;
http://www.pharsight.com/extranet/index.php?option=com_kunena&Itemid=55&func=view&catid=41&id=1021#
2033
(you'll need to sign up to access this free forum; where you can discuss and exchange uses.)
Best regards
Simon.
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