PharmPK Discussion - Salicylic acid Cmax

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On 11 Nov 2013 at 19:13:32, Jozef Al-Gousous (joalgous.aaa.uni-mainz.de) sent the message


Hi all!

Could somebody please provide me with data on the salicylic acid Cmax following the administration
of low doses of plain and enteric-coated aspirin tablets? And concerning the enteric coated, I will
be also very grateful if somebody has got data on the absorption lag time and tmax.

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On 12 Nov 2013 at 18:35:54, Daniel Sitar (sitar.-a-.cc.umanitoba.ca) sent the message


Please see following paper regarding enteric-coated ASA PK and approximately equivalent dose of
plain ASA.

Montgomery PR, Sitar DS (1986) Acetylsalicylic acid metabolites in blood and urine after plain and
enteric-coated tablets.  Biopharm Drug Disposit 7, 21-25.

Dr. Daniel S. Sitar
Editor in Chief, Journal of Clinical Pharmacology
Professor Emeritus
Dept of Internal Medicine (Clinical Pharmacology)
Dept of Pharmacology and Therapeutics

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