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Dear friends, January 27, 1998
I have undertaken a research project on "Polymorphism of hepatic cytochrome
P450 enzymes in a South Indian Population". We want to estimate the
levels of Dextromethrophan and dextrorphan for this
purpose. However I am unable to get "Dextrorphan" from India. I could not
find it in Sigma catalogue also.
I shall be grateful if any of you can send me some amount of dextrorphan
for our immediate use and also inform me the source and approximate cost.
Thanking you
Yours sincerely
Dr.C.Adithan
Chief Editor - IJP &
Professor of Pharmacology,
JIPMER,
Pondicherry - 605006,
India
email: adithan.-a-.biogate.com
Website: http://www.geocities.com/Athens/Delphi/2038
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[db - a few responses]
X-Sender: rasams.aaa.pop.service.ohio-state.edu
Mime-Version: 1.0
Date: Tue, 27 Jan 1998 17:44:57 -0500
To: PharmPK.at.pharm.cpb.uokhsc.edu
From: "Richard Sams PhD."
Subject: Re: PharmPK dextrorphan powder
Dear Dr. Adithan:
If you are using a chromatographic method to measure dextrorphan, you do not
necessarily need to obtain a standard of it. You could use an authentic
standard of levorphanol which is its optical isomer and which is
indistinguishable from it in chromatographic procedures unless you
incorporate a chiral step. Levorphanol is more readily available than
dextrorphan although it is a controlled substance in the US.
Sincerely,
Richard A. Sams, PhD
Professor and Laboratory Director
Analytical Toxicology Laboratory
College of Veterinary Medicine
The Ohio State University
Telephone: 614-292-5730
Fax: 614-292-4299
email address: sams.3.-at-.osu.edu
---
From: Robert Milne
To: "'PharmPK.-at-.pharm.cpb.uokhsc.edu'"
Subject: RE: PharmPK dextrorphan powder
Date: Wed, 28 Jan 1998 09:19:41 +1030
X-Priority: 3
MIME-Version: 1.0
Try the ICN Pharmaceuticals, Inc., 1997 catalogue page 310, catalogue
number 153741. Costs are given.
---
Date: Tue, 27 Jan 1998 20:19:47 -0800 (PST)
From: Richard Molitor
To: PharmPK.aaa.pharm.cpb.uokhsc.edu
cc: Multiple recipients of PharmPK - Sent by
Subject: Re: PharmPK dextrorphan powder
MIME-Version: 1.0
Hello Dr. Adithan:
The 1998 ICN product catalog has a listing for dextrorphan-o-tartrate for
$82.60/5gm. Their Web site is at http://www.icnpharm.com for further
information.
Cheers,
Richard Molitor, R.Ph.
http://www.angelfire.com/wa/pharmacist/index.html
---
X-Sender: prema.aaa.192.168.1.1
Date: Thu, 29 Jan 1998 08:42:34 -0500
To: PharmPK.-at-.pharm.cpb.uokhsc.edu
From: Chandrani Gunaratna
Subject: Re: PharmPK dextrorphan powder
Mime-Version: 1.0
Dear Dr. Adithan,
Dextrorphan D-tartrate is commercially available from RBI in USA.
Research Biochemicals International (RBI)
One Strathmore Road
Natick, MA 01760-2447
Phone: (508)651-8151
Fax: (508) 655-1359
E-mail: orders.-a-.resbio.com
Internet: http://www.callrbi.com
Their 1997/98 catalog lists the price for 500 mg as US $47.00.
Hope this information helps.
Chandrani Gunaratna, Ph.D.
Senior Research Chemist
Bioanalytical Systems
2701 Kent Avenue
West Lafayette, IN 47906
---
Date: Wed, 28 Jan 1998 08:56:41 -0500 (EST)
From: "Susan E. Shoaf"
Subject: Re: PharmPK dextrorphan powder
To: PharmPK.-a-.pharm.cpb.uokhsc.edu
Mime-Version: 1.0
On Tue, 27 Jan 1998, adithan wrote:
Dextrorphan D-tartrate 500 mg, #D-127, 47.00 from Research Biochemicals
International 508-651-8151 or 800 736-3690
They also have 3-methoxymorphinan hcl ,M-187, and 3-hydroxymorphinan
HBr, H-156.
Susan
shoaf.-at-.clinpharm.niaaa.nih.gov | National Institute on Alcohol Abuse and
I don't speak for NIAAA, | Alcoholism
that's for the PR office. |
[db - it looks like some of those catalogs we receive can be useful
sometimes ;-)]
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