Pharmacokinetic and Pharmacodynamic Resources

The purpose of this page is to provide links to information about the discipline of Pharmacokinetics and Pharmacodynamics.

"Pharmacokinetics is the study of the time course of drug and metabolite levels in different fluids, tissues, and excreta of the body, and of the mathematical relationships required to develop models to interpret such data." from Gibaldi, M. and Perrier, D. 1975 Pharmacokinetics, Marcel Dekker, page v.

PharmPK Listserve

If you wish to join the PharmPK forum please send me an e-mail at david@boomer.org. Thank you.

Messages can be sent as plain text messages, no attachments, to david.bourne@cuanschutz.edu.

Information in this area includes:

• Recent PK / PD Job Opportunities
• Software
• On-line Courses
  • Basic Pharmacokinetics by David Bourne
  • Pharmacokinetics - Advanced by David Bourne
  • Interactive Clinical Pharmacology using Flash by Dr Matt Doogue, Christchurch Hospital
  • Principles of Drug Disposition at University of Iowa by Craig K. Svensson et al.
  • Web Based Pharmacometrics Learning Resource provided by the American College of Clinical Pharmacology and the FDA
• Textbooks

  My Apps and eBooks by David Bourne
  Basic Pharmacokinetics v1.4 ($2.99 USD)	Pharmacy Math - Part 1 v1.5 ($2.99 USD)	Pharmacy Math - Part 2 v1.0 ($1.99 USD)

• Journals
• Summaries of Earlier PharmPK discussions

  PharmPK 1995 Discussions PharmPK 1996 Discussions PharmPK 1997 Discussions PharmPK 1998 Discussions PharmPK 1999 Discussions PharmPK 2000 Discussions PharmPK 2001 Discussions PharmPK 2002 Discussions PharmPK 2003 Discussions PharmPK 2004 Discussions PharmPK 2005 Discussions PharmPK 2006 Discussions PharmPK 2007 Discussions PharmPK 2008 Discussions PharmPK 2009 Discussions PharmPK 2010 Discussions PharmPK 2011 Discussions PharmPK 2012 Discussions PharmPK 2013 Discussions PharmPK 2014 Discussions PharmPK 2015 Discussions PharmPK 2016 Discussions Archive of Recent Messages and PharmPK Home at UCDenver Listserv (from June 2013) (password and login required - see FAQ above)

  Abbreviations seen in PharmPK Messages

  • Attachments from PharmPK discussions
  • PharmPK Discussion List Frequently Discussed Topics
  • Search the PharmPK archives
• Consensus Documents under development (project stalled somewhat ;-)
  • Once-Daily Dosing of Aminoglycosides
  • Continuous infusion of beta-lactam antibiotics: a potential strategy to improve parenteral antimicrobial therapy
• NONMEM Links
  • NONMEM page
  • A NONMEM ftp site at GloboMax (login as guest, aka anonymous)
  • NONMEM UsersNet Archive (Apr 1995 - Dec 2006) at Cognigen Corp
  • Summaries of NONMEM discussions (Apr 1999 - Jan 1996)
  • Setting up NONMEM under Mac OS X (2010, maybe a useful start - zip file)
  • PK/PD WWW site run by Steve Shafer
• Resource Facility for Population Kinetics (RFPK) Home Page
• PharmGKB, Pharmacogenetics and Pharmacogenomics Knowledge Base
• Phish-Pharm: A Searchable Database of Pharmacokinetics and Drug Residue Literature in Fish from the FDA
• Interspeciesinfo website from the Dutch Ministry of Health, Welfare and Sports
• Drugs and Toxic Chemicals in Breast Milk, Seminar on PBPK modeling of drugs and toxic chemicals in infants and Physiologically Based Pharmacokinetic Models And Biologically Based Pharmacodynamic Models Library of Published Models by Dr. Janusz Z. Byczkowski
• Pharmacology Corner - Pharmacology Animations blog by Flavio Guzman
• Human ATP-Binding Cassette Transporters
• Databases on the FDA Website
  • Inactive Ingredient Search for Approved Drug Products, FDA
• BioModels Database

Interactive Graphs

eBooks for iPad®/iPhone®/Mac®

iPhone®/iPad® Apps

Interactive Elements

Copyright 2001-18 David Bourne (david@boomer.org)